Modified clostridial toxins with enhanced translocation...

Details Modified clostridial toxins with enhanced translocation... Modified clostridial toxins with enhanced translocation...

2011-08-09

2011-08-09

Kam, Chih-Min (Department: 1656)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

C424S236100, C435S069700, C514S002600, C514S012200, C530S350000

Reexamination Certificate

active

07993656

ABSTRACT:
The invention provides modified Clostridial toxins comprising a Clostridial toxin enzymatic domain, a Clostridial toxin translocation domain, a translocation facilitating domain and an altered target domain; polynucleotide molecules encoding such modified Clostridial toxins; and methods of producing such modified Clostridial toxins.

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