Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2007-07-10
2007-07-10
Prouty, Rebecca E. (Department: 1652)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C435S091100, C435S209000, C435S069100, C800S265000, C800S279000, C800S280000, C800S300000
Reexamination Certificate
active
10721996
ABSTRACT:
Cellulose synthase (“CS”), a key enzyme in the biosynthesis of cellulose in plants is inhibited by herbicides comprising thiazolidinones such as 5-tert-butyl-carbamoyloxy-3-(3-trifluromethyl)phenyl-4-thiazolidinone (TZ), isoxaben and 2,6-dichlorobenzonitrile (DCB). Two mutant genes encoding isoxaben and TZ-resistant cellulose synthase have been isolated from isoxaben and TZ-resistantArabidopsis thalianamutants. When compared with the gene coding for isoxaben or TZ-sensitive cellulose synthase, one of the resistant CS genes contains a point mutation, wherein glycine residue 998 is replaced by an aspartic acid. The other resistant mutation is due to a threonine to isoleucine change at amino acid residue 942. The mutant CS gene can be used to impart herbicide resistance to a plant; thereby permitting the utilization of the herbicide as a single application at a concentration which ensures the complete or substantially complete killing of weeds, while leaving the transgenic crop plant essentially undamaged.
REFERENCES:
patent: 6495740 (2002-12-01), Arioli et al.
Heim et al., A second locus, lxr B1 inArabidopsis thaliana, that confers resitance to the herbicide isoxaben . Plant Physiol. , 1990 vol. 92 : 858-861.
Scheible et al., Modifications of cellulose synthase confer resistance to isoxaben and thiazolidinione herbicides inArabidopsislxr1 mutants. PNAS., 2001, vol. 98 (18): 1079-10084.
“Modifications of Cellulose Synthase Confer Resistance to Isoxaben and Thiazolidinone Herbicides inArbabidopsislxrl Mutants”, scheible, Wolf-Rudiger, et al.,Proc. Natl. Acad. Sci. vol. 98:18:10079-10084, Aug. 28, 2001.
Scheible Wolf
Somerville Chris R.
Gottlieb Paul A.
Lally Brian J.
Park Daniel D.
U.S. Department of Energy
LandOfFree
Modified cellulose synthase gene from Arabidopsis thaliana... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Modified cellulose synthase gene from Arabidopsis thaliana..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Modified cellulose synthase gene from Arabidopsis thaliana... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3798431