Modified bile acid conjugates, and their use as pharmaceuticals

Details Modified bile acid conjugates, and their use as pharmaceuticals Modified bile acid conjugates, and their use as pharmaceuticals

1994-03-10

1995-10-31

Datlow, Philip I.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

424528, 540 5, 540106, 540107, 540113, A61K 3158, C07J 4300

Patent

active

054629330

ABSTRACT:
Bile acid derivatives, processes for their preparation and use as pharmaceuticals Bile acid derivatives of the formula I

REFERENCES:
patent: 2441129 (1948-05-01), Berczeller
patent: 3937815 (1976-02-01), Bruzzese et al.
patent: 4418059 (1983-11-01), Lalezari
patent: 4499020 (1985-02-01), Lalezari
patent: 4925852 (1990-05-01), Kesseler et al.
patent: 4968790 (1990-11-01), DeVries et al.
Lehninger, Principles of Biochemistry, Worth Publishers, Inc., (1982), pp. 690-691.
Ho, N. F. H., "Utilizing Bile Acid Carrier mechanisms to Enhance Liver and Small Intestine Absorption," Annals new York Academy of Sciences 110:315-329 (1987).
Fieser, L. F. and Fieser, M., Steroids, pp. 3, 53-55, 64, 77, 79, 83 (Reinhold Pub. Corp., N.Y., 1959).

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