Modified baculovirus, its preparation process and its applicatio

Details Modified baculovirus, its preparation process and its applicatio Modified baculovirus, its preparation process and its applicatio

1994-12-14

1996-12-10

Guzo, David

Chemistry: molecular biology and microbiology

Treatment of micro-organisms or enzymes with electrical or...

Modification of viruses

4351721, 4353201, C12N 1566, C12N 1564

Patent

active

055830234

ABSTRACT:
The present invention describes modified baculoviruses possessing unique restriction endonuclease cleavage sites downstream of the promoter of the baculovirus viral inclusion, polyhedron and/or protein P10 genes and a method for obtaining such modified baculoviruses. Such modified baculoviruses are useful for the direct cloning of heterologous DNA into the unique endonuclease restriction sites and the consequent expression of the heterologous DNA inserted therein.

REFERENCES:
Muller et al. "Genetic Engineering", vol. 8. Eds, J. K. Setlow and A. Hollaender An Insect Baculovirus Host-Vector System for High Level Expression of Foreign genes, pp. 277-298.

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