Modified anti-CD52 antibody

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Monoclonal antibody or fragment thereof

Reexamination Certificate

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Details

C424S200100, C530S388220, C536S023530

Reexamination Certificate

active

10977369

ABSTRACT:
The present invention provides for modified forms of anti-CD52 antibodies with reduced numbers of potential T-cell epitopes that are expected to display decreased immunogenicity.

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Sequence search results for SEQ ID Nos.: 1 (pp. 1-5) and 2 (pp. 1-5).
VH and VL domain map for SEQ ID Nos.: 1 and 2 (1 page).
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Dyer, “The Role of CAMPATH-I Antibodies in the Treatment of Lymphoid Malignancies,”Seminars in Oncology, 26:52-57, 1999.

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