Modified (115-145) beta interferons

Details Modified (115-145) beta interferons Modified (115-145) beta interferons

1984-06-25

1988-04-19

Hazel, Blondel

Drug, bio-affecting and body treating compositions

Lymphokine

530351, 435 68, 4351723, 435811, A61K 4502, C07K 1300, C07K 1526, C12P 2100

Patent

active

047388455

ABSTRACT:
Modified beta interferons containing amino acid substitutions in the beta interferon amino acids 115 to 145 are described. These modified beta interferons exhibit changes in the antiviral, cell growth regulatory or immunomodulatory activities when compared with unmodified beta interferon.

REFERENCES:
patent: 4414150 (1983-08-01), Goeddel
patent: 4569908 (1986-02-01), Mark et al.
patent: 4588585 (1986-05-01), Mark et al.
Shepard et al., Nature, vol. 294, pp. 563-565, 1981.

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