Modified (1-28) beta interferons

Details Modified (1-28) beta interferons Modified (1-28) beta interferons

1984-06-22

1988-04-19

Hazel, Blondel

Drug, bio-affecting and body treating compositions

Lymphokine

530351, 435 68, 4351723, 435811, A61K 4502, C07K 1300, C07K 1526, C12P 2100

Patent

active

047388447

ABSTRACT:
Modified beta interferons containing amino acid substitutions in the beta interferon amino acids 1 to 28 are described. These modified beta interferons exhibit changes in the antiviral, cell growth regulatory or immunomodulatory activities when compared with unmodified beta interferon.

REFERENCES:
patent: 4414150 (1983-08-01), Goeddel
patent: 4569908 (1986-02-01), Mark et al.
patent: 4588585 (1986-05-01), Mark et al.
Shepard et al., Nature vol. 294, pp. 563-565, 1981.

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