Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Primate cell – per se
Reexamination Certificate
2008-01-15
2008-01-15
Ketter, James (Department: 1636)
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
Primate cell, per se
C435S320100
Reexamination Certificate
active
07319034
ABSTRACT:
Phosphorylated Apoptin is described. Apoptin is tumor-specifically phosphorylated and part of the Apoptin apoptotic pathway in tumor cells is elucidated. New therapeutic possibilities, for example, novel therapeutic compounds that can work alone or, sequentially to, or jointly with other known compounds. Also, the use of tumor-specifically phosphorylation of Apoptin for diagnostic purposes is described. Such a diagnostic purpose can, for example, be a method for detecting the presence of cancer cells or cells that are cancer prone or a method to identify a putative cancer inducing agent or a method for the in vitro treatment effect of Apoptin on tumor cells by testing the phosphorylation state of Apoptin. Even more, the invention provides possibilities to further elucidate the apoptotic pathway and to identify for example crucial mediators of phosphorylation in human tumor cells. Interfering with such a mediator could provide new anti-cancer therapies.
REFERENCES:
patent: 5491073 (1996-02-01), Noteborn et al.
patent: WO9503414 (1995-02-01), None
patent: WO 96/41191 (1996-12-01), None
patent: WO 98/46740 (1998-10-01), None
patent: WO 99/08108 (1999-02-01), None
patent: WO 99/28461 (1999-06-01), None
Donner Peter
Mumberg Dominik
Noteborn Mathieu Hubertus Maria
Rohn Jennifer Leigh
Ketter James
Leadd B.V.
TraskBritt
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