Modification of polypeptide structure

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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436501, 36441301, 364496, 364497, 364499, G01N 3353

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active

056795270

ABSTRACT:
Disclosed in the present application are methods for the identification of favored and suppressed patterns of hydrophobic and nonhydrophobic amino acids in naturally occuring proteins and polypeptides. Methods are disclosed which enable protein structure alteration based on information gained from hydrophobicity pattern analysis.

REFERENCES:
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Lu et al,, J. Immunol. 145: 899 (1990).
Lu et al., J. Biol. Chem. 266: 10054 (1991).
Vazquez, et al., J. Biol. Chem. 267: 1 (1992).

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