Modification of lignin synthesis in plants

Details Modification of lignin synthesis in plants Modification of lignin synthesis in plants

1995-05-26

2000-05-23

McElwain, Elizabeth F.

Multicellular living organisms and unmodified parts thereof and

Method of introducing a polynucleotide molecule into or...

800298, 536 236, A01H 500, C12N 1582

Patent

active

06066780&

ABSTRACT:
The synthesis of lignin by plants is controlled by transformation of the plant genome with a recombinant gene construct which contains the gene specifying an enzyme critical to the synthesis of a lignin precursor, which gene may be in antisense orientation so that it is transcribed to mRNA having a sequence complementary to the equivalent mRNA transcribed from the endogenous gene thus leading to suppression of lignin synthesis. If the recombinant gene has the lignin enzyme gene in normal, or "sense" orientation, increased production of the enzyme may occur when the insert is the full length DNA but suppression may occur it only a partial sequence is employed.

REFERENCES:
patent: 4394443 (1983-07-01), Weissman et al.
patent: 5034423 (1991-07-01), Jorgensen et al.
Napoli et al (1990) The Plant Cell 2: 279-289.
Grand et al (1985) Planta 163: 232-237.
Walter et al (1988) Proce. Natl Acad Sc USA 85:5546-5550.
Delaney et al (1988) Proc. Natl Acad Sci USA 85:4300-4304.
Sarni et al (1984) Eur. J. Biochem 139:259-265.
Bevan et al (1989) EMBO J. 8 (7):1899-1906.
Rhodes et al (1988) Science 240:204-207.
Van der Krol (1988) Nature 333:866-869.
Lewin, R. (1987) Science 237:1570.
Cannon et al, "Organ-specific modulation of gene expression in transgenic plants using antisense RNA", Plant Molecular Biology 1990, 15:39-47.
Crooke, Stanley T., M.D. (ed.) Antisense Research and Applications, CRC, pp. 125-148.
Bird et al, "Manipulation of Plant Gene Expression by Antisense RNA", Biotechnology and Genetic Engineering Reviews, vol. 9, Dec. 1991, pp. 207-227.
O'Malley et al, "Purification and Characterization of Cinnamyl Alcohol Dehydrogenase from Developing Xylem of Loblolly Pine, and its Role in Strategies to Modify the Lignin Content of Wood", J. Cellular Biochemistry, Abstracts 19th Annual Meetings, Mar. 31-Apr. 22, 1990, No. R 532, p. 355.
Schuch et al, "Transgenic plants having reduced lignin or lignin of altered quality", Chemical Abstracts, vol. 114, 1991, No. 114:222827m.
Loopstra et al, "Isolation of Genes with Enhanced Expression in Xylem Tissue of Loblolly Pine," J. Cellular Biochemistry, Abstracts 19th Annual Meetings, Mar. 31-Apr. 22, 1990, No. R 525, p. 353.
Grima-Pettenati et al, "Inhibition of Cinnamyl Alcohol Dehydrogenase Synthesis in Stably Transformed Tobacco Plants Expressing Antisense RNA", J. Cellular Biochemistry, Abstracts 19th Annual Meetings, Mar. 31-Apr. 22, 1990, No. R 511, p. 348.
O'Malley et al, "Purification, Characterization, Cloning of Cinnamyl Alcohol Dehydrogenase in Loblolly Pine (Pincus Taeda L.)", Plant Physiol. (1992) 98, 1364-1371.
Sarni et al, "Purification and properties of cinnamoyl-cocaxyme A reductase (EC 1.2.1.44) and clamamyl alcohol alcohol dehydrogenase (EC 1.1.1.1) from poplar stems (Populus euramericana)," Biological Abstracts, vol. 78, (1984) No. 14461, p. 1647.
Elkind et al, "Abnormal plant development and down-regulation of phenylpropanoid biosynthesis in transgenic tobacco containing a heterologous phenylalanine ammonia-lyase gene," Proc. Natl. Acad. Sci. U.S.A. vol. 878, Nov. 1990, pp. 9057-9061.
Rothstein et al, "Inhibition of Nopaline Synthase and Peroxidase Expression in Tobacco Expressing Antisense RNA" Plant Gene Transfer, 1990, pp. 135-141.
Halpin et al, "Purification and Characterization of Cinnamyl Alcohol Dehydrogenase from Tobacco Stems," Plant Physiol. 98 (1992) p. 12-16.
Halpin et al, "Manipulation of lignin quality by downregulation of cinnamyl alcohol dehydrogenase", The Plant Journal 6(3) 1994 p. 000-000.
Jacobs et al (1985) Nature 313:806-809.
Leonard et al (1984) Nature 311:626-631.
Matsudaira, P. (1987) J. Biol. Chem 262 (21):10035-10038.
Matsudaira, P. (1990), Methods in Enzymology 182:602-613.
Kim et al (1994) Plant Mol. Biol 24: 105-117.

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