Models for asthma guinea pig

Multicellular living organisms and unmodified parts thereof and – Nonhuman animal

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Details

800DIG4, 424 91, 4351723, C12N 1500, A61K 4900

Patent

active

056023022

ABSTRACT:
The present invention relates to a method of preparing bronchial hypersensitive or hyposensitive guinea pigs by selective breeding on the basis of bronchial sensitivity to inhalant chemicals inducing bronchoconstriction. The hypersensitive guinea pigs of the present invention are extremely useful as model animals for the study of bronchial asthma and allergic rhinitis and for the evaluation of efficacy of-antiasthmatics and antiallergic substances.

REFERENCES:
Watanabe (1980) Atherosclerosis 36, 261-268.
Ayitey-Smith (1974) J. Pharm. Pharmac. 26, 208-209.

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