Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage
Patent
1997-09-18
2000-08-22
Park, Hankyel
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving virus or bacteriophage
436506, 514 44, 5303894, 5303896, 435 724, 435 29, 435 39, 435810, 435974, C12Q 170, G01N 33564, A01N 4304, C07K 1600
Patent
active
061070203
ABSTRACT:
Methods and kits for diagnosing the presence of and prognosing the of stages of HIV disease, involving correlating rate of CD4% decline, CMC activity and plasma HIV RNA load, are disclosed. In particular, the methods and kits pertain to diagnosis and prognosis of disease progression in retroviral infections.
REFERENCES:
Ellaurie, M. et al. (1990) "Human Immunodeficiency Virus (HIV) Circulating Immune Complexes in Infected Children" AIDS Res. Hum. Retro.; 6(12):1437-41.
Ho, D. (1996) "Viral Counts Count in HIV Infection" Science; 272:1124-25.
Kovacs, J.A. (1995) "Increases in CD4 T Lymphocytes with Intermittent Courses of IL-2 in Patients with Human Immunodeficiency Virus Infection" N. Eng. J. Med.; 332:567-575.
Levy, J. et al. (1994) "Passive Hyperimmune Plasma Therapy in the Treatment of Acquired Immunodeficiency Syndrome: Results of a 12-month Multicenter Double-Blind Controlled Trial" Blood; 84(7):2130-35.
Pennisi, E. et al. (1996) "Eradicating HIV From a Patient: Not Just a Dream?" Science; 272:1884.
Schechter, M.T. et al. (1990) "Susceptibility to AIDS Progression Appears Early in HIV Infection" AIDS; 4:185-90.
Skowron, G. (1994) "HIV-1 env-Specific Cellular Cytotoxicity in HIV-1-Seropositive Mothers and Their Infants" AIDS Research and Human Retroviruses; 10(Suppl. 2):S79-82.
DeConti, Jr.,Esq. Giulio A.
Lauro, Esq. Peter C.
Park Hankyel
Roger Williams Hospital
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