Modafinil compound and cyclodextrin mixtures

Details Modafinil compound and cyclodextrin mixtures Modafinil compound and cyclodextrin mixtures

2006-11-28

2006-11-28

Maier, Leigh C. (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C514S618000

Reexamination Certificate

active

07141555

ABSTRACT:
Mixtures of a modafinil compound with a cyclodextrin, methods for their use, and compositions thereof are disclosed, along with complexes comprising a modafinil compound and a cyclodextrin which are taste-masked and suitable for oral consumption in an aqueous solution.

REFERENCES:
patent: 4177290 (1979-12-01), Lafon
patent: 4565807 (1986-01-01), Uekama et al.
patent: 4727064 (1988-02-01), Pitha
patent: 4927855 (1990-05-01), Lafon
patent: 5024997 (1991-06-01), Motola et al.
patent: 5180745 (1993-01-01), Lafon
patent: 5391576 (1995-02-01), Lafon
patent: 5618845 (1997-04-01), Grebow et al.
patent: 5843347 (1998-12-01), Nguyen et al.
patent: 5866162 (1999-02-01), Grattan
patent: 6077871 (2000-06-01), Campeta
patent: 6200968 (2001-03-01), Dickason et al.
patent: RE37516 (2002-01-01), Grebow et al.
patent: 6346548 (2002-02-01), Miller et al.
patent: 6455588 (2002-09-01), Scammell et al.
patent: 2 702 968 (1994-09-01), None
patent: WO 94/21371 (1994-09-01), None
Pitha, J. et al “Hydroxypropyl-b-cyclodextrin: preparation and characterization” Int. J. Pharm. (1986) vol. 29, pp. 73-82.
Hedges, A. “Industrial applicationf of Cyclodextrins” Chem. Rev. (1998) vol. 98, pp. 2035-2044.
Loftsson, T. et al “Pharmaceutical applications of cyclodextrins” J. Pharm. Sci. (1996) vol. 85, No. 10, pp. 1017-1025.
Spirichev, V. B. et al “Study of bioavailability of different forms of synthetic beta-carotene in volunteers” Vopr. Pitan. (1996) vol. 6, pp. 22-26 (abstract only).
Westerberg, G. et al “Beta-cyclodextrin reduces bioavailability of orally administered [3H]benzo[a]pyrene in the rat” J. Pharm. Sci. (2005).
Hostetler, J. et al “Effect of cyclodextrin on the pharmacology . . . ” Antimicrob. Agents Chemother. (1992) vol. 36, No. 2, pp. 477-480.
Nakanishi, K. et al “Effect of teh interaction of drug-beta-cyclodextrin complex with bile salts . . . ” Chem. Pharm. Bull. (1989) vol. 37, No. 1, pp. 211-214.
Szejtli, J. “Introduction and general overview of cyclodextrin chemistry” Chem. Rev. (1998) vol. 98, pp. 1743-1753.
CyDex presentation on Captisol® (http://www.cydexinc.com/maxdocs/Cyclodextrin-derivatives.pdf, accessed Apr. 6, 2006).
Rambert, F.A. et al.,Neuropschychopharmacology, 1994, 10(3S), 169S.
Uekama, K. et al.,CRC Critical Reviews in Therapeutic Drug Carrier Systems, 1987, 3(1), 1-40.
Parrish, M.A.,Cyclodextrins.
Loftsson, T.,Pharmaceutical Technology, 1999, 12, 40-50.
Duchêne, D. et al.,Drug Dev. Ind. Pharm., 1986, 12(11-13), 2193-2215.
Szente, L. et al.,Journal of Inclusion Phenomena, 1984, 2, 631-636.
Pagington, J.S.,Chemistry in Britain, 1987, 455-458.
Wen-lu, S. et al.,Chemosphere, 1999, 38(4), 693-698.
Ammar, H. O. et al.,Pharmazie, 1995, 50, 805-808.
Masson et al.,Journal of Controlled Release, 1999, 59, 107-118.
Nakanishi, K. et al.,Chem. Pharm. Bull., 1992, 40, 1252-1256.
Challa et al., AAPS PharmSciTech, 2005, 6, E329-E357.

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