Mobile phase dilution scheme for enhanced chromatography

Details Mobile phase dilution scheme for enhanced chromatography Mobile phase dilution scheme for enhanced chromatography

2011-03-22

2011-03-22

Therkorn, Ernest G (Department: 1776)

Liquid purification or separation

With means to add treating material

Chromatography

C210S656000, C210S659000

Reexamination Certificate

active

07909994

ABSTRACT:
A method and device for increasing the loading capacity of a chromatography column through dilution of a mobile phase at the head of the column. A strong mobile phase is provided for dissolving a sample. A sample is injected into the strong mobile phase, and subsequently diluted with a weak mobile phase. The resulting sample-containing weak mobile phase is passed through a chromatography column for retention and separation of the components of the sample.

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