Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues
Reexamination Certificate
2002-05-03
2009-02-10
Salimi, Ali R. (Department: 1648)
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
C530S350000, C536S023720
Reexamination Certificate
active
07488791
ABSTRACT:
The invention concerns a mixture of peptides derived from the E6 and/or E7 proteins of a papillomavirus involved in cervix of uterus cancer, such as HPV16, HPV18, HPV30, HPV31, HPV32, HPV33, HPV34, HPV35, HPV39, HPV40, HPV42, HPV43, HPV44, HPV45, HPV51, HPV52, HPV56, HPV57, and HPV58, for example, as well as its uses as medicine (in immunogenic compositions, capable of stimulating the production of anti-HPV T CD4+ lymphocytes in vivo and hence useful for vaccination against uterine of uterus cancer and in other cancers) or as diagnostic reagent of HPV-specific T lymphocytes, in particular for assessing the immune condition of patients. The invention also concerns a mixture of peptides derived from E6 and/or E7 proteins of a papillomavirus involved in benign skin lesions (for example warts), such as HPV10, HPV3 or HPV4 and its uses as medicine.
REFERENCES:
patent: 2005/0100928 (2005-05-01), Hedley et al.
patent: 000523391 (1992-06-01), None
patent: 00/75336 (2000-12-01), None
Isabelle Bourgault-Villada, et al. “Identification In Humans Of HPV-16 E6 and E7 Protein Epitopes Recognized By Cytolytic T Lymphocytes In Association With HLA-818 and Determination of the HLA-B18-Specific Binding Motif.”European Journal Immunology. vol. 30, 2000, pp. 2281-2289.
Maaike E. Ressing, et al. “Human CTL Epitopes Encoded By Human Papillomavirus Type 16 E6 and E7 Identified Through In Vivo and In Vitro Immunogenicity Studies of HLA-A*0201-Binding Peptides1.”Journal of Immunology. vol. 154, 1995, pp. 5934-5943.
Azoury-Ziadeh et al. “T-helper epitopes identified within the E6 transforming protein of cervical cancer-associated human Papillomavirus type 16.” Viral Immunol. 12: 297-312, 1999.
Bourgault-Villada Isabelle
Guillet Jean-Gerard
Maillere Bernard
Pouvelle-Moratille Sandra
Commissariat a l''Energie Atomique
Institut National de la Sante et de la Recherche Medicale (INSER
Morgan & Lewis & Bockius, LLP
Salimi Ali R.
LandOfFree
Mixture of peptides derived from E6 and/or E7 papillomavirus... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Mixture of peptides derived from E6 and/or E7 papillomavirus..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Mixture of peptides derived from E6 and/or E7 papillomavirus... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4075799