Mixture of calcium carbonate and calcium-.alpha.-p-chlorophenoxy

Details Mixture of calcium carbonate and calcium-.alpha.-p-chlorophenoxy Mixture of calcium carbonate and calcium-.alpha.-p-chlorophenoxy

1973-06-15

1976-04-20

Rosen, Sam

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Monoclonal antibody or fragment thereof

260521H, 424317, 424357, 424360, 424362, 424365, A61K 3119, A61K 3300

Patent

active

039520960

ABSTRACT:
Calcium .alpha.-p-chlorophenoxyisobutyrate, particularly as its novel monohydrate, when combined with about one to two parts by weight of calcium carbonate in oral dosage form for use in mammals, and especially man, provides a safe and effective composition for reducing elevated blood levels of cholesterol, triglycerides and/or low density lipoproteins and/or increasing fibrinolytic activity and/or decreasing platelet aggregation. A preferred embodiment is a capsule containing 500 mgm. calcium carbonate and 250 or 500 mgm. crystalline calcium .alpha.-p-chlorophenoxyisobutyrate monohydrate having the empirical formula C.sub.10 H.sub.10 ClO.sub.3 Ca.sub.1/2.H.sub.2 O.

REFERENCES:
patent: 3262850 (1966-07-01), Jones et al.
chemical Abstracts I (Maibach), Vol. 66, 103983q (1967).
Chemical Abstracts II, Vol. 73, 13070e, (1970).

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