Mixed vaccine against infections by pseudomonas aeruginosa

Details Mixed vaccine against infections by pseudomonas aeruginosa Mixed vaccine against infections by pseudomonas aeruginosa

1977-01-28

1979-06-05

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

424 87, 424 94, A61K 3748, A61K 3902

Patent

active

041573897

ABSTRACT:
A three component-mixed vaccine against infections caused by Pseudomonas aeruginosa which comprises as the antigens an infection-protective common antigen OEP (Original Endotoxin Protein) obtained from P. aeruginosa, an elastase toxoid obtained from P. aeruginosa and a protease toxoid obtained from P. aeruginosa.

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Lusis et al., Vet. Bull. 41(3): 169-177, Mar. 1971, "Pseudomonas aeruginosa".
Markley and Smallman, J. Bact. 96(4): 867-874, Oct. 1968, "Protection by Vaccination Against Pseudomonas Infection After Thermal Injury".
Jones Journal of Hygeine, (Cambridge), 67:241-247 (1969), "Detoxification of an Immunogenic Fraction from a Culture Filtrate of Pseudomonas aeruginosa".
Liu et al., J. Inf. Dis. 128(4): 520-526, Oct. 1973, "Exotoxins of Pseudomonas aeruginosa III Characteristics of Antitoxin A".
Pavlovskis et al., Microbiology, pp. 252-256, (1975), "Pseudomonas aeruginosa Exotoxin".
Callahan, Infection and Immunity, 14(1): 55-61, (Jul. 1976), "Pseudomonas aeruginosa Exotoxin: Purification by Preparative Polyacrylamide Gel Electrophoresis and the Development of a Highly Specific Antitoxin Serum".

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