Mixed phase chromatographic compositions

Details Mixed phase chromatographic compositions Mixed phase chromatographic compositions

1980-05-05

1981-11-03

Kyle, Deborah L.

Compositions

Preservative agents

Anti-oxidants or chemical change inhibitants

55386, 2101982, 2101983, 252430, B01D 1508

Patent

active

042985005

ABSTRACT:
The mixed phase packing material of this invention, enables rapid separation of multi-sited biopolymers. This separation is achieved by "tailoring" the distance between organo-silyl groups covalently bonded to the rigid support at the Angstrom distance needed for reversible separation of the biopolymers of interest and "capping" other sterically available active sites on the support with a relatively inert compound.

REFERENCES:
patent: 3505785 (1970-04-01), Kirkland
patent: 3983299 (1976-09-01), Regnier
patent: 4029583 (1977-06-01), Chang et al.
patent: 4108603 (1978-08-01), Regnier et al.
patent: 4111838 (1978-09-01), Schaeffer et al.
patent: 4180383 (1979-12-01), Johnson
patent: 4199330 (1980-04-01), Nestrick et al.
patent: 4242227 (1980-12-01), Nestrick et al.
"Chromosorb .RTM.LC-7", a Technical Data Sheet of Johns-Manville Filtration and Minerals Division.
Borovansky et al., "Chromatographic Separation of Melanosomes", J. Chromatog., 134, (1977), 230-234.
Shechter, "Separation of Proteins . . . ", Anal. Biochem., 58, 30-38, (1974).
Regnier et al., "Glycerolpropylsilane Bonded Phases . . . ", J. Chrom. Sci., 14, (1976), 316.
Darling et al., "Rapid Purification of an RNA Tumor Virus . . . ", J. Chromatog., 131, (1977), 383-390.
Hiatt et al., "Treatment of Controlled Pore Glass . . . ", J. Chromatog., 56, (1977), 362-364.
Haller, "Chromatography on Glass of Controlled Pore Size", Nature, 206, (1965), pp. 693-696.
Mizutani et al., "Adsorption of Cationic Biological Materials . . . ", Anal. Biochem, 83, (1977), 216-221.

Affiliated with

Also associated with

Rating

Mixed phase chromatographic compositions does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Mixed phase chromatographic compositions, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Mixed phase chromatographic compositions will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1063707