Mixed mode microfluidic systems

Chemistry: electrical and wave energy – Processes and products – Electrophoresis or electro-osmosis processes and electrolyte...

Reexamination Certificate

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C204S451000

Reexamination Certificate

active

07101467

ABSTRACT:
Methods and systems that employ hybrid fluid flow profiles for optimized movement of materials through channel networks. These systems employ hybrid pressure-based and electrokinetic based flow systems for moving materials through interconnected channel networks while maintaining interconnection among the various channel segments. In particular, the invention is generally directed to channel networks where flow in a first channel segment is driven by pressure flow with its consequent parabolic flow profile, while flow in an interconnected channel segment is dominated by electrokinetic flow with its consequent plug flow profile. The invention also provides channel networks wherein fluid flow in channel segments is driven by both pressure and electric field and the multiple species contained in a fluid plug are separated (and can be concentrated) by altering the applied pressure and electric fields in the various channel segments of the channel networks.

REFERENCES:
patent: 5726404 (1998-03-01), Brody et al.
patent: 6695009 (2004-02-01), Chien et al.
patent: 2003/0230486 (2003-12-01), Chien et al.
patent: WO-02/10732 (2002-02-01), None
patent: WO-03/006133 (2003-01-01), None

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