Drug – bio-affecting and body treating compositions – Designated organic nonactive ingredient containing other... – Carboxylic acid or salt thereof
Patent
1992-06-30
1994-05-24
Waddell, Frederick E.
Drug, bio-affecting and body treating compositions
Designated organic nonactive ingredient containing other...
Carboxylic acid or salt thereof
514786, 514558, 514560, A61K 4700
Patent
active
053149211
ABSTRACT:
A composition is disclosed containing non-esterified fatty acids having 14-18 carbon atoms, monoglycerides which are monoesters of glycerol and fatty acids having 14-18 carbon atoms, lysophosphatidylcholine in which the fatty acid moiety has 14-18 carbon atoms and bicarbonate. The compositions can optionally also contain bile salts. These compositions form submicron size colloidal particles and can act as vehicles for transporting orally administered drugs, sources of calories in the form of readily absorbable fats and as particles for topical application to the skin. A method of making these particles is also described.
REFERENCES:
patent: 3169094 (1965-02-01), Wretlind
patent: 4035513 (1977-07-01), Kumano
patent: 4156719 (1979-03-01), Sezaki et al.
patent: 4280996 (1981-07-01), Okamoto et al.
patent: 4325942 (1982-04-01), Taki et al.
patent: 4454113 (1984-06-01), Hemker
patent: 4464400 (1984-08-01), Kimura et al.
patent: 4874795 (1989-10-01), Yesair
Tso, P., et al., Am. J. Physiol. 250(6 Pt 1): 715-726, Jun. 1986.
Staggers, J. E., Dissertation Abstr. Internat. B (Sci. and Engineer) 44(10): 3069 (218 pp) 1984.
Muranishi, S. et al., International Journal of Pharmaceutics, 2: 101-111 (1979).
Muranishi, S. et al., Journal of Pharmaceutic Dynamics, 2: 286-294 (1979).
Muranishi, N. et al., International Journal of Pharmaceutics, 4: 271-279 (1980).
Taniguchi, K. et al., International Journal of Pharmaceutics, 4: 219-228 (1980).
Serajuddin, A. T. M. et al., Pharmaceutical Research, 221-224 (1985).
Yoshikawa, H. et al., Pharmaceutical Research, 249-250 (1985).
Muranishi, S., Pharmaceutical Research, 108-118 (1985).
Chem. Abst., 102: 154829, (1985)-Ohashi et al.
Tso P. et al., Biochimica et Biophysica Acta 528, 364-372 (1978).
PCT/US/91/05716, Yesair, International Search Report, Jan. 30 1992.
Moezie Minna
Waddell Frederick E.
LandOfFree
Mixed lipid-bicarbonate colloidal particles does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Mixed lipid-bicarbonate colloidal particles, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Mixed lipid-bicarbonate colloidal particles will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1973164