Surgery – Miscellaneous – Methods
Reexamination Certificate
2005-04-12
2005-04-12
Isabella, David J. (Department: 3738)
Surgery
Miscellaneous
Methods
C424S093100
Reexamination Certificate
active
06877514
ABSTRACT:
A method of inducing tolerance without whole body irradiation.
REFERENCES:
patent: 5597563 (1997-01-01), Beschorner
patent: 5658564 (1997-08-01), Sykes et al.
patent: 5806529 (1998-09-01), Reisner et al.
patent: 5876708 (1999-03-01), Sachs
patent: 6006752 (1999-12-01), Sykes
patent: 6296846 (2001-10-01), Sachs et al.
patent: 6412492 (2002-07-01), Sykes
patent: 6514513 (2003-02-01), Sykes
patent: WO9313785 (1993-07-01), None
Anasetti et al., Effect of HLA compatibility on engraftment of bone marrow transplants in patients with leukemia or lymphoma, 1989, vol. 320:197-204. New England Journal of Medicine.
Aversa et al., Successful engraftment of T-cell-depleted haploidentical “three-loci” incompatible transplants in leukemia patients by addition of recombinant human granulocyte colony-stimulating factor-mobilized peripheral blood progenitor cells to bone marrow inoculum, 1994, vol. 84:3948-3955, Blood.
Bachar-Lustig et al., Megadose of T cell-depleted bone marrow overcomes MHC barriers in sublethally irradiated mice, 1995, vol 1:1268-1273, Nature Med.
Brecher et al., Special proliferative sites are not needed for seeding and proliferation of transfused bone marrow cells in normal syngeneic mice, 1982, vol. 79:5085-5087, PNAS USA.
Lee et al., Natural killer cells weakly resist engraftment of allogeneic long-term multilineage-repopulating hematopoietic stem cells, 1996, vol. 61:125-132, Transplantation.
O'Reilly et al., Transplantation of marrow depleted T cells by soybean lectin agglutination and E-rosette depletion: major histocompatibility complex related graft resistance in leukemic transplant recipients, 1985, vol.; 17:455-459, Transplant. Proc.
Stewart et al., Long-term engraftment of normal and post-5-fluoracil murine marrow into normal nonmyeloablated mice, 1993, vol. 81:2566-2571, Blood.
Tomita et al., Myelosuppressive conditioning is required to achieve engraftment of pluripotent stem cells contained in moderate doses of syngeneic bone marrow, 1994, vol. 83:939-948, Blood.
Tomita et al., Additional mAb injections can replaced thymic irradiation to allow induction of mixed chimerism and tolerance in mice receiving bone marrow transplantation after conditioning with anti-T cell mAbs and 3 Gy whole body irradiation, 1996, vol. 61:469-477, Transplantation.
Tomita et al., Mechanism by which additional monoclonal antibody injections overcome the requirement ofr thymic irradiation to achieve mixed chimerism in mice receiving bone marrow translantation after conditioning with anti-T cell mAbs and 3 Gy whole body irradiation, 1996, vol. 61:477-485, Transplantation.
Kahan, “Drug Therapy, Cyclosporine”NE J. Medicine321(25):1725-1738 (1989).
Fung et al., “Conversion of Liver Allograft Recipients From Cyclosporine to FK 506-Based Immunosuppression: Benefits and Pitfalls”Transplantation Proc. 23(1):14-21 (1991).
Makowka et al., The Development of Brequinar as an Immunosuppressive Drug for TransplantationImmunological Reviews136:51-70 (1993).
Sykes et al., “Xenograft Tolerance”Immunological Reviews141:246-276 (1994).
Starzl et al., “The Biological Basis of and Strategies for Clinical Xenotransplantation”Immunological Reviews141:213-244 (1994).
W. Beschorner et al., “Recruitment of Semiallogeneic Dendritic Cells to The Thymus During Post-Cyclosphorine Thymic Regeneration”,Transplantation, vol. 60, No. 11, pp. 1326-1330, 1995.
Reisner et al., “Bone Marrow Transplantation Across HLA Barriers By Increasing The Number Of Transplanted Cells”,Immunology Today, vol. 16, No. 9, pp. 437-440, 1995.
W. Beschorner et al., “Recruitment of Semiallogeneic Dendritic Cells to The Thymus During Post-Cyclosphorine Thymic Regemeration”,Transplantation, vol. 60, No. 11, pp. 1326-1330, 1995.
Reisner et al., “Bone marrow Transplantation Across HLA Barriers By Increasing The Number Of Transplanted Cells”Immunology Today, vol. 16, No. 9, pp. 437-440, 1995.
Kahan, “Drug Therapy, Cyclosporine”NE J. Medicine321(25): 1725-1738 (1989).
Fung et al., “Conversion of Liver Allograft Recipients From Cyclosporine to FK 506-Based Immunosuppression: Benefits and Pitfalls”Transplantation Proc.23(1):14-21 (1991).
Makowka et al., The Development of Brequinar as an Immunosuppressive Drug for TransplantationImmunological Reviews136:51-70 (1993).
Sykes et al., “Xenograft Tolerance”Immunological Reviews141:246-276 (1994).
Starzl et al., “The Biological Basis of and Strategies for Clinical Xenotransplantation”Immunological Reviews141:213-244 (1994).
Ramshaw et al., “High levels of engraftment with a single infusion of bone marrow cells into normal unprepared mice”, Biol. Of Blood and Marrow Transpl. 1:74-80 (1995).
Shizuru et al., “Transplantation of purified hematopoietic stem cells: Requirements for overcoming the barriers of allogeneic engraftment”, Biol. Of Blood and Marrow Transpl. 2:3-14 (1996).
Anasetti et al., Effect of HLA compatibility on engraftment lymphoma, 1989, vol. 320:197-204. New England Journal of Medicine.
Aversa et al., Successful engraftment of T-cell-depleted haploidentical “three-loci” incompatible transplants in leukemia patients by addition of recombinant human granulocyte colony-stimulating factor-mobilized peripheral blood progenitor cells to bone marrow inoculum, 1994, vol. 84:3948-3955, Blood.
Bachar-Lustig et al., Megadose of T cell-depleted bone marrow overcomes MHC barriers in sublethally irradiated mice, 1995, vol. 1:1268-1273, Nature Med.
Brecher et al., Special proliferative sites are not needed for seeding and proliferation of transfused bone marrow cells in normal syngeneic mice, 1982, vol. 79:5085-5087, PNAS USA.
Lee et al., natural killer cells weakly resist engraftment of allogeneic long-term multilineage-repopulating hematopoietic stem cells, 1996, vol. 61:125-132, Transplantation.
O'Reilly et al., Transplantation of marrow depleted T cells by soybean lectin agglutination and E-rosette deletion: major histocompatibility complex-related graft resistance in leukemic transplant recipients, 1985, vol.; 17:455-459, Transplant. Proc.
Stewart et al., Long-term engraftment of normal and post-5-fluoracil murine marrow into normal nonmycloablated mice, 1993; vol. 81:2566-2571, Blood.
Tomita et al., Myelosuppressive conditioning is required to achieve engraftment of pluripotent stem cells contained in moderate doses of syngeneic bone marrow, 1994, vol. 83:939-948, Blood.
Tomita et al., Additional mAB injections can replaced thymic irradiation to allow induction of mixed chimerism and tolerance in mice receiving bone marrow transplantation after conditioning with anti-T cell mABs and Gy whole body irradiation, 1996, vol. 61:469-477, Transplantation.
Tomita et al., Mechanism by which additional monoclonal antibody injections overcome the requirement ofr thymic irradiation to achieve mixed chimerism in mice receiving bone marrow transplantation after conditioning with anti-T cell mABs and 3 Gy whole body irradiation, 1996, vol. 61:477-485, Transplantation.
Kawai et al., “Mixed Allogeneic Chimerism and Renal Allograft Tolerance in Cynomolgus Monkeys”, Transplantation, vol. 59, pp. 256-262.
Sykes et al., “Induction of High Levels of Allogeneic Hematopoietic Reconstruction and Donor-Specific Tolerance Without Myelosuppressive Conditioning”, Nature Medicine, vol. 3, No. 7, pp. 783-787.
Fuchimoto et al., “Mixed Chimerism and Tolerance Without Whole Body Irradiation in a Large Animal Model”, The Journal of Clinical Investigation, vol. 105, No. 12, pp. 1779-1789.
Fish & Richardson P.C.
Isabella David J.
The General Hospital Corporation
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