Mixable combination for generating a suspension of stable...

Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Ultrasound contrast agent

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C424S009500, C424S009510

Reexamination Certificate

active

06896875

ABSTRACT:
Gas or air filled microbubble suspensions in aqueous phases usable as imaging contrast agents in ultrasonic echography. They contain laminarized surfactants and, optionally, hydrophilic stabilizers. The laminarized surfactants can be in the form of liposomes. The suspensions are obtained by exposing the laminarized surfactants to air or a gas before or after admixing with an aqueous phase.

REFERENCES:
patent: 3615972 (1971-10-01), Morehouse
patent: 3650831 (1972-03-01), Jungermann
patent: 3900420 (1975-08-01), Sebba
patent: 3968203 (1976-07-01), Spitzer
patent: 4027007 (1977-05-01), Messina
patent: 4192859 (1980-03-01), Mackaness et al.
patent: 4224179 (1980-09-01), Schneider
patent: 4229360 (1980-10-01), Schneider et al.
patent: 4235871 (1980-11-01), Papahadjopoulos et al.
patent: 4265251 (1981-05-01), Tickner
patent: 4276885 (1981-07-01), Tickner et al.
patent: 4316391 (1982-02-01), Tickner
patent: 4370349 (1983-01-01), Evans
patent: 4442843 (1984-04-01), Rasor et al.
patent: 4466442 (1984-08-01), Hilmann et al.
patent: 4544545 (1985-10-01), Ryan et al.
patent: 4572203 (1986-02-01), Feinstein
patent: 4657756 (1987-04-01), Rasor et al.
patent: 4681119 (1987-07-01), Rasor et al.
patent: 4684479 (1987-08-01), D'Arrigo
patent: 4718433 (1988-01-01), Feinstein
patent: 4774958 (1988-10-01), Feinstein
patent: 4832941 (1989-05-01), Berwing et al.
patent: 4844882 (1989-07-01), Widder et al.
patent: 4859363 (1989-08-01), Davis et al.
patent: 4900540 (1990-02-01), Ryan et al.
patent: 4927623 (1990-05-01), Long
patent: 4957656 (1990-09-01), Cerny et al.
patent: 5049322 (1991-09-01), Devissaguet et al.
patent: 5088499 (1992-02-01), Unger
patent: 5089181 (1992-02-01), Hauser
patent: 5123414 (1992-06-01), Unger
patent: 5137928 (1992-08-01), Erbel et al.
patent: 5141738 (1992-08-01), Rasor et al.
patent: 5147631 (1992-09-01), Glajch et al.
patent: 5149319 (1992-09-01), Unger
patent: 5190982 (1993-03-01), Erbel
patent: 5195520 (1993-03-01), Schlief
patent: 5205287 (1993-04-01), Erbel
patent: 5209720 (1993-05-01), Unger
patent: 5228446 (1993-07-01), Unger
patent: 5271928 (1993-12-01), Schneider
patent: 5283067 (1994-02-01), Geller et al.
patent: 5312615 (1994-05-01), Schneider
patent: 5352436 (1994-10-01), Wheatley
patent: 5364612 (1994-11-01), Goldenberg
patent: 5380411 (1995-01-01), Schlief
patent: 5380519 (1995-01-01), Schneider
patent: 5393524 (1995-02-01), Quay
patent: 5409688 (1995-04-01), Quay
patent: 5413774 (1995-05-01), Schneider
patent: 5425366 (1995-06-01), Reinhardt et al.
patent: 5445813 (1995-08-01), Schneider
patent: 5501863 (1996-03-01), Rossling et al.
patent: 5529766 (1996-06-01), Klaveness
patent: 5531980 (1996-07-01), Schneider
patent: 5536489 (1996-07-01), Lohrmann
patent: 5536490 (1996-07-01), Klaveness
patent: 5552133 (1996-09-01), Lambert et al.
patent: 5556610 (1996-09-01), Yan et al.
patent: 5558856 (1996-09-01), Klaveness et al.
patent: 5567413 (1996-10-01), Klaveness
patent: 5567414 (1996-10-01), Schneider
patent: 5593687 (1997-01-01), Rössling et al.
patent: 5599523 (1997-02-01), Beller et al.
patent: 5601085 (1997-02-01), Ostensen
patent: 5639443 (1997-06-01), Schutt et al.
patent: 5643553 (1997-07-01), Schneider
patent: 5658551 (1997-08-01), Schneider
patent: 5670135 (1997-09-01), Schroder
patent: 5711933 (1998-01-01), Bichon et al.
patent: 5716597 (1998-02-01), Lohrmann et al.
patent: 5730954 (1998-03-01), Albayrak et al.
patent: 5776429 (1998-07-01), Unger et al.
patent: 5874062 (1999-02-01), Unger
patent: 4065189 (1990-03-01), None
patent: 7098291 (1991-10-01), None
patent: 1232837 (1988-02-01), None
patent: 1239092 (1988-07-01), None
patent: 2077383 (1993-03-01), None
patent: A 41 27 442 (1993-02-01), None
patent: 0 077 752 (1983-04-01), None
patent: 0122624 (1984-10-01), None
patent: A 131 540 (1985-01-01), None
patent: 0131540 (1985-10-01), None
patent: 0 245 019 (1987-11-01), None
patent: A 324 938 (1989-07-01), None
patent: 0 324 938 (1989-07-01), None
patent: 0327490 (1989-08-01), None
patent: 0441468 (1990-02-01), None
patent: 0357163 (1990-03-01), None
patent: 359 246 (1990-03-01), None
patent: 359 246 (1990-03-01), None
patent: A 458 745 (1991-11-01), None
patent: 0 467 031 (1992-01-01), None
patent: 0494615 (1992-07-01), None
patent: A 554 213 (1993-04-01), None
patent: 0123235 (1994-10-01), None
patent: 1044680 (1966-10-01), None
patent: 213 5647 (1984-09-01), None
patent: 253115 (1996-01-01), None
patent: WO-A-802365 (1980-11-01), None
patent: WO 8002365 (1980-11-01), None
patent: WO 8402838 (1984-08-01), None
patent: WO-A-8502772 (1985-07-01), None
patent: WO 887365 (1988-10-01), None
patent: WO 8905160 (1989-06-01), None
patent: WO 8906978 (1989-08-01), None
patent: WO 8910118 (1989-11-01), None
patent: WO 9001952 (1990-03-01), None
patent: WO 9109629 (1991-07-01), None
patent: WO 9112823 (1991-09-01), None
patent: WO9112823 (1991-09-01), None
patent: WO 9115244 (1991-10-01), None
patent: WO 9205806 (1992-04-01), None
patent: WO A 9217212 (1992-10-01), None
patent: WO 9217212 (1992-10-01), None
patent: WO 9217213 (1992-10-01), None
patent: WO 9217514 (1992-10-01), None
patent: WO9218164 (1992-10-01), None
patent: WO 9218164 (1992-10-01), None
patent: WO 9219273 (1992-11-01), None
patent: WO 9221382 (1992-12-01), None
patent: WO 9222247 (1992-12-01), None
patent: WO 935819 (1993-04-01), None
patent: WO9305819 (1993-04-01), None
patent: WO 9306869 (1993-04-01), None
patent: WO 9317718 (1993-09-01), None
patent: WO 9416739 (1994-08-01), None
patent: 842800 (1984-04-01), None
patent: 910961 (1991-11-01), None
deJong et al Ultrasonics 1992 vol. 30 No. 2 pp. 95-103 Absorption and scatter of encapsulated gas etc.
deJong et al. Ultrasonics 1991 vol. 29 Jul. pp. 324-330 Principles and recent developments in ultrasound etc.
Bleeker et al 1990 J. Ultrasound Med 9:461-471, 1990 pp. 462-471 On the Application of Ultrsonic Contrast etc.
Feinstein et al JACC vol 16, No. 2 8/90:316-24 Safety and Efficacy of a New Transpulmonary Ultrasound etc.
Amer Hearts Assn Monograph Circulation Part II vol. 72 No. 1 10/85 Abstracts of the 58thScientific Sessions.
Bleeker et al J. Acoust. Soc. Am 87 (4) 4/90 pp. 1792-1797 Ultrasonic Characterization of Albunex® etc.
Epstein et al J. Chem. Physics vol. 18, No. 11, 11/50 On the Stability of Gas Bubbles in Liquid-Gas Solutions.
Meltzer et al Ultrasound in Med & Biol vol. 7, No. 4 pp. 377-384 1981 Trasmission of Ultrasonic Contrast etc.
Violante et al Investigative Radiology vol. 26 Nov. Supp 1991 Particle-Stabilized Bubbles for Enhanced etc.
Ohta et al Jpn J Med Ultrasonics vol. 18 No. 4 (1991) Effect of the Contrast Agent and the Agitation Method etc.
Feinstein et al Am J of Physiologic Imaging 1:12-18 (1986) Myocardial Contrast Echocardiography etc.
Widder et al AJR:147, 8/86 Microbubbles as a Contrast Agent for Neurosonography and Ultrasound- etc.
Schlief Current Opinion in Radiology 1991, 3:198-207 Ultrasound Contrast Agents.
Fobbe et al Furtschr Rontgenstr 154.3 (1991)242-245 Farbkodierte Duplexsonographic und Ultra- etc.
Ophir et al Ultrasound in Med & Biol vol. 15 No. 4 pp. 319-333 1989 Contrast Agents in Diagnostic Ultrasound.
Swanson, pp. 682-687, “Chapter 22: Enhancement Agents for Ultrasound: Fundamentals,” Pharmaceuticals In Medical Imaging, (EDS. Swanson et al., MacMillian Publishing Company, New York, 1990).
Lincoff et alIntravitreal Longevity of Three Perfluorocarbon Gases, Arch. Ophthalmology,98:1610-1611 (1980).
Lincoff et alIntravitreal Expansion of Perfluorocarbon Bubbles, Arch. Ophthalmology,98:1646 (1980).
Lincoff et alThe Perfluorocarbon Gases in the Treatment of Retinal Detachment, Ophthalmology,90(5):546-551 (1983).
Lincoff et alPerfluoro-n-butane: A Gas for Maximum Duration Retinal Tamponade, Arch. Ophthalmology,101:460-463 (1983).
Gardner et al (1988) “A Survey of Intraocular Gas Use in North America,”Arch. Ophthalmol.,106:1188-1189.
Biochemistry/Ed. Stryer—2 Ed., San Francisco, Freeman, pp. 208-209 (1981).
Concise Encyclopedia Of Polymer Sci. and Engin., Wiley, pp. 12-13 (1990).
Encyclopedia of Polymer Science and Engineering, 2nd ed., 10, p. 95,

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Mixable combination for generating a suspension of stable... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Mixable combination for generating a suspension of stable..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Mixable combination for generating a suspension of stable... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3434629

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.