Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-08-15
2010-06-08
Shameem, Golam M (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C548S240000
Reexamination Certificate
active
07732472
ABSTRACT:
The present invention relates to dihydroisoxazoles that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also relates to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.
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Fraley Mark E.
Garbaccio Robert M.
Hartman George D.
Beeler Nicole M.
Merck & Co. , Inc.
Merck Sharp & Dohme Corp.
Murhard David A.
Shameem Golam M
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