Mitotic kinesin inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C548S110000

Reexamination Certificate

active

07625936

ABSTRACT:
The present invention relates to dihydropyrazole compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.

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Cancer [online], [retrieved on Jul. 6, 2007]. Retrieved from the internet, URL http://www.nlm.nih.gov/medlineplus/cancer.html>.
Cancer [online], [retrieved on Jul. 6, 2007], retrieved from the internet, URL; http://en.wikipedia.org/wiki/Cancer.
Huang, et al. Organic Letters (2000) vol. 2, No. 18 pp. 2833-2836.
Brodey, J et al., Journal of Pharmacology and Experimental Therapeutics, vol. 140, pp. 8-18 (1963), “An electrographic study of psilocin and 4-methyl-a-methyl tryptamine”.

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