Mitotic kinesin inhibitors

Details Mitotic kinesin inhibitors Mitotic kinesin inhibitors

2003-12-16

2009-11-24

Andres, Janet L (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C546S226000

Reexamination Certificate

active

07622489

ABSTRACT:
The present invention relates to tetrahydropyridine compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.

REFERENCES:
patent: 5559238 (1996-09-01), Guzzi et al.
patent: 2006/0058327 (2006-03-01), Fraley et al.
patent: WO03/105855 (2003-12-01), None
Hcaplus 1999:287417, “A study on the reactivity of 3-methyl-2,6-diphenyl-4-piperidone”, Reddy et. al.
Prostakov, et al. Chemical Abstracts, abstract No. 151974t, vol. 87, No. 19, p. 572 (1977).
Lansbury, JACS, 90(2), pg. 536-7 (1968).
Bruderer, et al., Helv. Chim. Acta., 47, pp. 1852-1859 (1964).
D. A. Comins, Tetrahedron Letters, 33, pp. 6299-6302 (1992).
T. D. Sokolova, et al., Chemistry of Heterocyclic Compounds, 33(6), pp. 676-679 (1997).
K. D. Praliev, et al., Khim. -Farm. Zh., 17(9), pp. 1053-1055 (1983).
N. Yokoyama, et al., J. Med. Chem., 22(5), pp. 537-553 (1979).

Affiliated with

Also associated with

Rating

Mitotic kinesin inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Mitotic kinesin inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Mitotic kinesin inhibitors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4099787