Mitotic kinesin inhibitors

Details Mitotic kinesin inhibitors Mitotic kinesin inhibitors

2003-12-16

2009-11-24

Andres, Janet L. (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C544S406000

Reexamination Certificate

active

07622468

ABSTRACT:
The present invention relates to tetrahydropyridine compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.

REFERENCES:
patent: 5559238 (1996-09-01), Guzzi et al.
patent: 2006/0052611 (2006-03-01), Fraley et al.
patent: WO03/105855 (2003-12-01), None
Hcaplus 112:97889, “Dissociative ionization of substituted piperidines”, Stashenko et. al, Khimiya Geterotsiklicheskikh Soedinenii (1989), (6), 795-800.
Hcaplus 1999:287417, “A study on the reactivity of 3-methyl-2,6-diphenyl-4-piperidone”, Reddy et. al., Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1999 38 B(2), 141-147.
Lansbury, JACS, 90 (2), p. 536-7 (1968).
Bruderer, et al., Helv. Chim. Acta., 47, pp. 1852-1859 (1964).
D. A. Comins, Tetrahedron Letters, 33, pp. 6299-6302 (1992).
T. D. Sokolova, et al., Chemistry of Heterocyclic Compounds, 33(6), pp. 676-679 (1997).
K. D. Praliev, et al., Khim. -Farm. Zh., 17(9), pp. 1053-1055 (1983).
N. Yokoyama, et al., J. Med. Chem., 22(5), pp. 537-553 (1979).
Hohenlohe-Oehringen, K, Database XP002513864, No. 1964:45609, vol. 94, No. 6, pp. 1208-1216, ISSN: 0026-9247.

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