Mitotic kinesin inhibitors

Details Mitotic kinesin inhibitors Mitotic kinesin inhibitors

2007-11-27

2007-11-27

McKane, Joseph K. (Department: 1609)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C514S212010, C514S218000, C514S222200, C514S228800, C514S241000, C514S247000, C514S277000, C514S359000, C514S423000, C544S002000, C544S003000, C544S063000, C544S179000, C544S180000, C546S001000, C546S112000, C546S184000, C548S125000, C548S146000, C548S206000, C548S215000, C548S240000, C548S250000, C548S255000, C548S262200, C548S300100, C548S356100, C548S400000, C548S416000, C548S542000

Reexamination Certificate

active

10517576

ABSTRACT:
The present invention relates to dihydropyrazole compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.

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