Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-06-13
2006-06-13
Balasubramanian, Venkataraman (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S266220, C514S212080, C514S227800, C514S230500, C544S287000, C544S060000, C544S105000, C540S485000, C540S492000
Reexamination Certificate
active
07060705
ABSTRACT:
The present invention relates to quinazolinone compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.
REFERENCES:
patent: 3322756 (1967-05-01), Ruschig et al.
patent: 3984555 (1976-10-01), Amschler et al.
patent: 1 584 579 (1969-12-01), None
patent: WO 98 26664 (1998-06-01), None
patent: WO 01 30768 (2001-05-01), None
patent: WO 01 81346 (2001-11-01), None
patent: WO 01 98278 (2001-12-01), None
patent: WO 03 070701 (2003-08-01), None
Mayer et al., Science 286: 971-974, 1999.
Bergnes et al., Curr. Top. Med. Chem. 5(2), 127-145, 2005.
Sakowicz et al., Cancer Research 64, 3276-3280, 2004.
DeBonis et al., Molecular Cancer Therapeutics, 3(9), 1079-1090, 2004.
Wood et al., Current Opinion in Pharmcology 1, 370-377, 2001.
Cancer Research 64, pp. 3276-3280, May 1, 2004, by R. Sakowicz, et al.
J. Med Chem., vol. 42, pp. 3203-3209 (1999), by A. Kumar Debnath, et al.
J. Med. Chem, vol. 11, No. 2, pp. 392-395, (1968), by C.M. Gupta, et al.
J. Indian Chem. Soc., 68(3), pp. 142-143, 1991, by S. Saxena, et al.
Fraley Mark E.
Hoffman William F.
Balasubramanian Venkataraman
Daniel Mark R.
Merck & Co. , Inc.
Muthard David A.
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