Mitomycin derivatives

Details Mitomycin derivatives Mitomycin derivatives

1989-09-07

1991-11-26

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548422, C07D48714, A61K 3140

Patent

active

050683497

ABSTRACT:
Novel mitomycin derivatives are characterized by a substituent on the C.sub.6 -methyl group. The mitomycin derivatives exhibit anti-tumor and antibacterial activity and have low toxicity.

REFERENCES:
patent: 4880825 (1989-11-01), Kasai et al.
patent: 4927943 (1990-05-01), Vyas et al.
Chemical Abstracts, vol. 113, 131886t (1990).
Patent Abstracts of Japan, vol. 3, No. 142 (C-65)(161), Nov. 24, 1979; & JPA 54-122797 (Kyowa Hakko Kogyo K.K.), Sep. 22, 1979 (Cat. D).
Patent Abstracts of Japan, vol. 4, No. 178 (C-14)(26), Jun. 11, 1980; & JPA 55-45322 (Kyowa Hakko Kogyo K.K.), Mar. 31, 1980 (Cat. D).
Patent Abstracts of Japan, vol. 4, No. 178 (C-34)(660), Dec. 10, 1980; & JPA-55-118396 (Kyowa Hakko Kogyo K.K.), Sep. 11, 1980 (Cat. D).

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