Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Fungus – except allergen – or component thereof or substance...
Patent
1980-11-13
1984-07-17
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Fungus, except allergen, or component thereof or substance...
A61K 3140
Patent
active
044605994
ABSTRACT:
Compounds of the formula, I, ##STR1## wherein: Y is hydrogen or lower alkyl; and X is a thiazolamino radical, a furfurylamino radical or a radical of the formula, ##STR2## in which R, R.sup.1, and R.sup.2 are the same or different and selected from the group consisting of hydrogen and lower alkyl, and R.sup.3 is selected from the group consisting of lower alkenyl, halo-lower alkenyl, lower alkynyl, lower akloxycarbonyl, thienyl, formamyl, tetrahydrofuryl and benzene sulfonamide.
Also disclosed are novel methods for treatment of neoplastic disease states in animals, which methods comprise administering a therapeutically effective amount of a compound of the formula, Ia, ##STR3## wherein: Y is hydrogen or lower alkyl; and Z is a thiazolamino radical, a furfurylamino radical, a cyclopropylamino radical, a pyridylamino radical, or a radical of the formula, ##STR4## in which R.sup.4, R.sup.5, and R.sup.6 are the same or different and selected from the group consisting of hydrogen and lower alkyl, and R.sup.7 is selected from the group consisting of lower alkenyl, halo-lower alkenyl, lower alkynyl, lower alkoxycarbonyl, halo-lower alkyl, hydroxy-lower alkyl, pyridyl, thienyl, formamyl, tetrahydrofuryl, benzyl, and benzene sulfonamide.
REFERENCES:
patent: 3332944 (1967-07-01), Cosulich et al.
patent: 3410867 (1968-11-01), Matsui et al.
patent: 3429894 (1969-02-01), Matsui et al.
patent: 3450705 (1969-06-01), Matsui et al.
patent: 3514452 (1970-05-01), Matsui et al.
patent: 4231936 (1980-11-01), Nakano et al.
patent: 4268676 (1981-05-01), Remers
Daus Donald G.
Teoli, Jr. William A.
University Patents Inc.
LandOfFree
Mitomycin analogs does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Mitomycin analogs, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Mitomycin analogs will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1490690