Mitomycin analogs

Details Mitomycin analogs Mitomycin analogs

1983-12-15

1986-10-14

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

544372, 544 60, 546143, 546161, 546133, 546153, 546271, 548126, 548127, 548128, 548134, 548138, 548181, 548222, 548255, 548266, 548371, 548372, 548374, 548422, C07D48704, A61K 3140

Patent

active

046173897

ABSTRACT:
Antineoplastic compounds of the formula, IIa, ##STR1## wherein: Y is hydrogen or lower alkyl; and Z is a lower alkoxy substituted quinolinylamino radical, a cyano substituted pyrazolylamino radical or a mono- or di-lower alkyl substituted thiazolamino radical, or

REFERENCES:
patent: 3332944 (1967-07-01), Cosulich et al.
patent: 3410862 (1968-11-01), Matsui et al.
patent: 3429894 (1969-02-01), Matsui et al.
patent: 4268676 (1981-05-01), Remers
patent: 4460599 (1984-07-01), Remers
Burger, ed., Medicinal Chemistry, 3rd ed., Wiley-Interscience (1970), pp. 65, 67, 71, 75.
Merk Index, 9th ed., Merk and Co., 1976, pp. 807-808, Abstract #6060.
Burger, ed., Medicinal Chemistry, Third ed., Wiley-Interscience, N.Y., (1970) pp. 72-74.

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