Mite protein

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Amino acid sequence disclosed in whole or in part; or...

Reexamination Certificate

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C530S300000, C530S324000

Reexamination Certificate

active

07105163

ABSTRACT:
The present invention relates to a novel major mite antigen, which according to the invention has been isolated and sequenced for the first time. More specifically, said antigen is a protein originating from the miteSarcoptes scabiei. Thus, the invention relates to said antigen as well as to the encoding nucleic acid as defined in the claims. Further, the invention also relates to advantageous uses of the novel protein and/or functional fragments thereof, e.g. in immunological testing, such as in ELISA methods, as well as in the preparation of vaccines.

REFERENCES:
patent: 5302527 (1994-04-01), Birkett et al.
patent: 6171800 (2001-01-01), Hsu
patent: 0 473 111 (1991-08-01), None
patent: A 07112999 (1996-01-01), None
patent: A 08301788 (1997-03-01), None
Plotkin et al Vaccines WB Saunders Co. Philadelphia, 1988, p. 571.
Medline accession No. 99113129, Moustafa EH et al, “The Relation Between Scabies and Hypersensitivity to Antigens of House Dust Mites and Storage Mites,”J. Egypt Soc. Parasitol, v. 28, No. 3, 1998 pp. 777-787.

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