Misuse-resistive transdermal opioid dosage form

Details Misuse-resistive transdermal opioid dosage form Misuse-resistive transdermal opioid dosage form

1991-06-14

1992-09-22

Page, Thruman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Web, sheet or filament bases; compositions of bandages; or...

424484, 424486, A61K 970, A61K 31485

Patent

active

051495384

ABSTRACT:
A misuse-resistive dosage form for the transdermal delivery of opioid comprises, in combination, 1) one or more opioid permeable to the skin, 2) delivery means permeable to said opioid, 3) one or more antagonist for said opioid releasable upon ingestion or solvent immersion, and 4) impermeable barrier means separating said opioid and said antagonist.

REFERENCES:
patent: 3996934 (1976-12-01), Zaffaroni
patent: 4464378 (1984-08-01), Hussain
patent: 4573995 (1986-03-01), Chen et al.
patent: 4588580 (1986-05-01), Gale et al.
patent: 4626539 (1986-12-01), Aungst et al.
patent: 4806341 (1989-02-01), Chien et al.
patent: 4917676 (1990-04-01), Heiber et al.
patent: 4935428 (1990-06-01), Lewis

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