Optics: measuring and testing – Blood analysis
Reexamination Certificate
2004-09-09
2009-12-08
Nguyen, Sang (Department: 2886)
Optics: measuring and testing
Blood analysis
C356S246000, C356S337000, C356S436000, C436S063000, C436S173000
Reexamination Certificate
active
07630063
ABSTRACT:
A system for scattered light and simultaneous multi-color (e.g., greater than sixteen colors) fluorescence light detecting, and for analyzing, classifying and identifying biological particles and items of interest. A sample to be tested may be entered in a disposable microfluidic cartridge which in turn is insertable in a portable, hand-holdable, or wearable miniaturized cytometer instrument. The present system may be incorporated in the cytometer instrument. It may have significant application relative to biological warfare, environmental substances, the medical field and other fields.
REFERENCES:
patent: 3721824 (1973-03-01), Bristol
patent: 3774042 (1973-11-01), Engel
patent: 3822095 (1974-07-01), Hirschfeld
patent: 3976862 (1976-08-01), Curbelo
patent: 4284412 (1981-08-01), Hansen et al.
patent: 4293221 (1981-10-01), Kay et al.
patent: 4478076 (1984-10-01), Bohrer
patent: 4478077 (1984-10-01), Boher
patent: 4501144 (1985-02-01), Higashi et al.
patent: 4651564 (1987-03-01), Johnson et al.
patent: 4683159 (1987-07-01), Bohrer et al.
patent: 4695034 (1987-09-01), Shimizu et al.
patent: 4714345 (1987-12-01), Schrader
patent: 4745279 (1988-05-01), Karkar et al.
patent: 4838688 (1989-06-01), Rhoads
patent: 4874949 (1989-10-01), Harris et al.
patent: 4911616 (1990-03-01), Laumann, Jr.
patent: 4983359 (1991-01-01), Tomioka et al.
patent: 4989978 (1991-02-01), Groner
patent: 5017497 (1991-05-01), Gerard de Grooth et al.
patent: 5050429 (1991-09-01), Nishimoto et al.
patent: 5078581 (1992-01-01), Blum et al.
patent: 5082242 (1992-01-01), Bonne et al.
patent: 5085562 (1992-02-01), van Lintel
patent: 5096388 (1992-03-01), Weinberg
patent: 5108623 (1992-04-01), Cangelosi et al.
patent: 5129794 (1992-07-01), Beatty
patent: 5159397 (1992-10-01), Kosaka et al.
patent: 5171132 (1992-12-01), Miyazaki et al.
patent: 5176358 (1993-01-01), Bonne et al.
patent: 5185265 (1993-02-01), Steen et al.
patent: 5185641 (1993-02-01), Igushi et al.
patent: 5194909 (1993-03-01), Tycko
patent: 5219278 (1993-06-01), van Lintel
patent: 5224843 (1993-07-01), van Lintel
patent: 5244537 (1993-09-01), Ohnstein
patent: 5247339 (1993-09-01), Ogino
patent: 5323999 (1994-06-01), Bonne et al.
patent: 5367474 (1994-11-01), Auer et al.
patent: 5378633 (1995-01-01), von Behrens et al.
patent: 5441597 (1995-08-01), Bonne et al.
patent: 5452878 (1995-09-01), Gravesen et al.
patent: 5492833 (1996-02-01), Rodriguez et al.
patent: 5528045 (1996-06-01), Hoffman et al.
patent: 5567627 (1996-10-01), Lehnen
patent: 5570193 (1996-10-01), Landa et al.
patent: 5601080 (1997-02-01), Oppenheimer
patent: 5616501 (1997-04-01), Rodriguez
patent: 5633724 (1997-05-01), King et al.
patent: 5683159 (1997-11-01), Johnson
patent: 5684575 (1997-11-01), Steen
patent: 5716852 (1998-02-01), Yager et al.
patent: 5723341 (1998-03-01), Truett
patent: 5726751 (1998-03-01), Altendorf et al.
patent: 5736410 (1998-04-01), Zarling et al.
patent: 5739902 (1998-04-01), Gjelsnes et al.
patent: 5757476 (1998-05-01), Nakamoto et al.
patent: 5784157 (1998-07-01), Gorfinkel et al.
patent: 5793485 (1998-08-01), Gourley
patent: 5799030 (1998-08-01), Brenner
patent: 5822170 (1998-10-01), Cabuz et al.
patent: 5828450 (1998-10-01), Dou et al.
patent: 5836750 (1998-11-01), Cabuz
patent: 5837547 (1998-11-01), Schwartz
patent: 5863502 (1999-01-01), Southgate et al.
patent: 5880474 (1999-03-01), Norton et al.
patent: 5888823 (1999-03-01), Matsumoto et al.
patent: 5893722 (1999-04-01), Hibbs-Brenner et al.
patent: 5901939 (1999-05-01), Cabuz et al.
patent: 5922210 (1999-07-01), Brody et al.
patent: 5932100 (1999-08-01), Yager et al.
patent: 5946083 (1999-08-01), Melendez et al.
patent: 5948684 (1999-09-01), Weigl et al.
patent: 5971158 (1999-10-01), Yager et al.
patent: 5972710 (1999-10-01), Weigl et al.
patent: 5974867 (1999-11-01), Forster et al.
patent: 6007775 (1999-12-01), Yager
patent: 6032689 (2000-03-01), Tsai et al.
patent: 6046807 (2000-04-01), Chandler
patent: 6078390 (2000-06-01), Bengtsson
patent: 6082185 (2000-07-01), Saaski
patent: 6097485 (2000-08-01), Lievan
patent: 6106245 (2000-08-01), Cabuz
patent: 6109889 (2000-08-01), Zengerie et al.
patent: 6133995 (2000-10-01), Kubota
patent: 6139800 (2000-10-01), Chandler
patent: 6179586 (2001-01-01), Herb et al.
patent: 6184607 (2001-02-01), Cabuz et al.
patent: 6215221 (2001-04-01), Cabuz et al.
patent: 6221671 (2001-04-01), Groner et al.
patent: 6228652 (2001-05-01), Rodriguez et al.
patent: 6237619 (2001-05-01), Maillefer et al.
patent: 6240944 (2001-06-01), Ohnstein et al.
patent: 6249341 (2001-06-01), Basiji et al.
patent: 6281975 (2001-08-01), Munk
patent: 6312393 (2001-11-01), Abreu
patent: 6382228 (2002-05-01), Cabuz et al.
patent: 6549275 (2003-04-01), Cabuz et al.
patent: 6683314 (2004-01-01), Oostman et al.
patent: 6791086 (2004-09-01), Russell
patent: 6887711 (2005-05-01), Diem et al.
patent: 1001326 (1999-05-01), None
patent: WO95/27199 (1995-03-01), None
patent: WO99/60397 (1999-04-01), None
patent: WO01/09598 (2000-07-01), None
http://www.micronics.net/tsensor.htm, pp. 1-4, downloaded Jun. 14, 2000.
http://www.micronics.net/hfilter.htm, pp. 1-3, downloaded Jun. 14, 2000.
http://www.micronics.net/mcytometry.htm, pp. 1-4, downloaded Jun. 14, 2000.
http://www.micronics.net/orcafluidics.htm, pp. 1-4, downloaded Jun. 14, 2000.
Altendorf et al., “Implementation Of Novel Optical Detection Methods For Clinically Important Blood Analytes Using Microfabricated Flow Structures (T-Sensors™)”, MicroTAS 98, Banff, Canada, Apr. 1998.
Altendorf et al., “Differential Blood Cell Counts Obtained Using A Microchannel Based Flow Cytometer”, Solid State Sensors & Actuators, vol. 1, 531, 1997.
Altendorf et al., “Microfabrication Technology For Research And Diagnostics, Silicon Microchannel Optical Flow Cytometry”, SPIE Proceedings, Biomedical Optics 96, Jan. 1996.
Altendorf et al., “Results Obtained Using A Prototype Microfluidics-Based Hematology Analyzer”, SPIE Biomedical Optics 97, 1997.
Cabuz, et al., “Mesoscopic Sampler Based on 3D Array of Electrostatically Activated Diaphragms”, Transducers '99, The 10th International Conference on Solid-State Sensors and Actuators, Digest of Technical Papers, vol. 2, Jun. 7-10, 1999.
Darling et al., “Integration Of Microelectrodes With Etched Microchannels For In-Stream Electrochemical Analysis”, MicroTAS 98, Banff, Canada, Apr. 1998.
Hatch et al., “Microfluidic Approaches To Immunoassays”, SPIE conference on Micromachining and Microfabrication Symposium at Santa Clara, CA, Sep. 20-22, 1999.
Huang. et al., “Development Of A Flow Cytometry Based Miniature Chemical Fluid Analysis System Using Fluorescent Microbeads”, SPIE Biomedical Optics, BIOS 97, conference proceedings, 1997.
Lehman et al., “High-Frequency Modulation Characteristics of Red VCSELs”, Electronics Letters, Feb. 13, 1997, vol. 33(4), pp. 298-300. Copyright 1997 IEE.
Ohnstein et al., “Micromachined Silicon Microvalve”, Proceedings of MEMS, 1990, IEEE Micro Electromechanical Systems, Napa Valley, California, Feb. 11-14, 1990, pp. 95-98.
Roulet et al., “Fabrication of Multilayer Systems Combining Microfluidic and Microoptical Elements for Fluorescence Detection,” Journal of Microelectromechanical Systems, vol. 10, No. 4, pp. 482-491, Dec. 2001.
Shapiro, “Practical Flow Cytometry”, third edition, 1995, p. 237.
Strzelecka et al., “Parallel Free-Space Optical Interconnect Based on Arrays of Vertical-Cavity Lasers and Detectors with Monolithic Microlenses”, Applied Optics, v. 37(14), May 10, 1998, pp. 2811-2821. Copyright 1998 Optical Society of America.
Terstappen, et al., “Four-Parameter White Blood Cell Differential Counting Based on Light Scattering Measurements”, Alan R. Liss, Inc., Cytometery 9:39-43, 1988.
Weigl et al., “Silicon-microfabricated diffusion-based optical chemical sensor,” Sensors and Actuators, B 38-39, pp. 452-457, 1997.
Weigl et al., “Diffusion-Based Optical Chemical Detecti
Fritz Bernard S.
Padmanabhan Aravind
Fredrick Kris T.
Honeywell International , Inc.
Nguyen Sang
LandOfFree
Miniaturized cytometer for detecting multiple species in a... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Miniaturized cytometer for detecting multiple species in a..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Miniaturized cytometer for detecting multiple species in a... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4126659