Mineralocorticoid receptor antagonists and methods of use

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C544S139000

Reexamination Certificate

active

07994164

ABSTRACT:
The present invention provides a compound of Formula (I):or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising a compound of Formula (I) in combination with a suitable carrier, diluent, or excipient; and methods for treating physiological disorders, particularly congestive heart failure, hypertension, diabetic nephropathy, or chronic kidney disease, comprising administering a compound of Formula (I), or a pharmaceutically acceptable salt thereof.

REFERENCES:
patent: 4072756 (1978-02-01), Arlesheim et al.
patent: 4999363 (1991-03-01), Oshima et al.
patent: 5024912 (1991-06-01), Neishi et al.
patent: 5378701 (1995-01-01), Ohshima et al.
patent: 5395610 (1995-03-01), King
patent: 0 345 747 (1989-12-01), None
patent: WO 99/33786 (1999-07-01), None
patent: WO 00/59884 (2000-10-01), None
patent: 2004052847 (2004-06-01), None
patent: WO 2004/052847 (2004-06-01), None
patent: 2005066153 (2005-07-01), None
patent: WO 2005/066161 (2005-07-01), None
patent: 2005110992 (2005-11-01), None
patent: WO 2006/015259 (2006-02-01), None
patent: 2006053024 (2006-05-01), None
patent: 2008053300 (2008-05-01), None
patent: 2008119918 (2008-10-01), None
patent: 2009080725 (2009-07-01), None
patent: 2009080730 (2009-07-01), None
patent: 2009094157 (2009-07-01), None
patent: 2010104721 (2010-09-01), None
Byrn et al., Solid-Sate Chemistry of Drugs, Second Edition, 1999, pp. 233-247.
Cheng et al., “Synthesis and Structure-Activity Relationships of 9-Substituted Acridines as Endothelia-A Receptor Antagonists,”Bioorg. Med. Chem. Let., vol. 6, No. 24, pp. 2999-3002 (1996).
Jadhav, “Discovery of orally bioavailable, non-steroidal mineralocorticoid receptor antagonists: A tale of three platforms,” slides for MR Antagonist Atlants ACS Meeting, Mar. 27, 2006.
Jadhav, Discovery of First, Orally Bioavailable, Non-Steroidal Mineralcorticoid Receptor Antagonists, slides, Feb. 11, 2003.
International Search Report and Written Opinion/ISA of the International Searching Authority of International Application No. PCT/US2008/085997, Mailing Date Mar. 27, 2009.
Reply to Written Opinion for International Application No. PCT/US2008/085997, Oct. 2009.
Notification of Transmittal of the International Preliminary Report on Patentability for International Application No. PCT/US2008/085997, Mar. 2010.

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