Mineralized collagen

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Scleroproteins – e.g. – fibroin – elastin – silk – etc.

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106 35, 106124, 106645, 106691, 128DIG8, 424423, A61K 3712, C07K 1520, C08H 106, C08L 8900

Patent

active

052311694

ABSTRACT:
Mineralized collagen is prepared by forming calcium phosphate mineral under mild agitation in situ in the presence of dispersed collagen fibrils. A stable composition is obtained with desirable physical characteristics mimicking the characteristics of bone.

REFERENCES:
patent: 3443261 (1969-05-01), Battista et al.
patent: 3968567 (1976-07-01), Nevins
patent: 4172128 (1979-10-01), Thiele et al.
patent: 4780450 (1988-10-01), Sauk et al.
patent: 4795467 (1989-01-01), Piez et al.
patent: 4880610 (1989-11-01), Constantz
Glimcher, Phil. Trans. R. Soc. Long. B. 304, 479-508 (1984).
Lowenstam and Weiner, On Biomineralization, (1988), pp. 149-158.

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