Mimetic insect pyrokinin analogs for insect control

Details Mimetic insect pyrokinin analogs for insect control Mimetic insect pyrokinin analogs for insect control

1996-08-22

1998-08-18

Krass, Frederick

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 16, 514 17, 514 18, 514 21, 530300, 530323, 530329, 530330, 530345, 530858, A01N 3718, A61K 3828

Patent

active

057958572

ABSTRACT:
Novel pseudopeptide analogs of the insect pyrokinin neuropeptide family which possess biological activity mimicking that of the naturally occurring neuropeptides are disclosed. By addition of a hydrophobic moiety to an active portion of the pyrokinin peptides, analogs are produced which exhibit an overall amphiphilic nature and which are capable of penetrating the insect cuticle while still retaining biological activity. The analogs may be used for insect control by disrupting the reproductive, developmental, and/or digestive processes normally regulated by pryrokinins in insects.

REFERENCES:
patent: 5032576 (1991-07-01), Raina et al.
Chemical Abstracts 125:159037, "Potent Pheromonotropic/Myotropic Activity of a Carboranyl Pseudopeptide Analog of the Insect Pyrokinin/PBAN Neuropeptide Family", 1996.
Chemical Abstracts 123:139491, "Pseudopeptides of the Pyrokinin/PBAN Insect Neuropeptide Family", 1995.

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