Mimetic insect kinin analogs for insect control

Details Mimetic insect kinin analogs for insect control Mimetic insect kinin analogs for insect control

1996-12-13

1998-08-11

Levy, Neil S.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Biocides; animal or insect repellents or attractants

424406, 514 17, 514 18, 514803, 530330, 930 20, 930320, A01N 2502

Patent

active

057924660

ABSTRACT:
Novel pseudopeptide analogs of the insect kinin neuropeptide family which possess biological activity mimicking that of the naturally occurring neuropeptides are disclosed. By substituting a sterically hindered amino acid which is compatible with a turn conformation, for the Xaa.sup.2 amino acid of the insect kinin C-terminal pentapeptide (i.e. Ser, Pro, or Ala), analogs are produced which exhibit resistance to degradation by angiotensin converting enzyme (ACE) while still retaining biological activity. The analogs may be used for insect control by disrupting the diuretic and/or myotropic activity in insects.

REFERENCES:
patent: 5589460 (1996-12-01), Abajian et al.

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