Milling process for the production of finely milled...

Details Milling process for the production of finely milled... Milling process for the production of finely milled...

2006-05-09

2006-05-09

Page, Thurman K. (Department: 1618)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

C424S400000, C514S463000

Reexamination Certificate

active

07041318

ABSTRACT:
The present invention is a method of milling materials to form a fine powder with a median particle size below 10 micrometer which is suitable for inhalation and which has substantially no amorphous content generated during milling. The method is particularly suitable for milling materials which are soft. The method comprises milling the material in a fluid energy mill at reduced temperature using helium, or helium mixed with another gas, as milling fluid. Temperatures of −30° C. or less are used.

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