Chemistry: analytical and immunological testing – Composition for standardization – calibration – simulation,... – Preservative – buffer – anticoagulant or diluent
Patent
1992-05-19
1993-03-23
Johnston, Jill A.
Chemistry: analytical and immunological testing
Composition for standardization, calibration, simulation,...
Preservative, buffer, anticoagulant or diluent
422 1, 426326, 4263302, 426335, 426532, 426654, 436 23, 436176, 514 31, A23C 308, G01N 100
Patent
active
051963442
ABSTRACT:
An antimicrobial composition for the preservation of milk samples required for analysis. The composition comprises 2-bromo-2-nitropropane-1,3-diol and natamycin, in effective amounts to prevent spoilage of the milk for a period of at least 5 to 10 days. The amount of 2-bromo-2-nitropropane-1,3-diol for a 50 ml milk sample is preferably 6-12 mg and the amount of natamycin is preferably 0.3-0.6 mg. The composition is preferably employed in the form of a tablet containing a suitable filler and usually other ingredients. In a method of preserving milk samples, the 2-bromo-2-nitropropane-1,3-diol and natamycin may be added separately or simultaneously (e.g. in admixture). The composition and method provide a way of preserving milk samples without the health problems associated with conventional preservatives such as dichromates and without the need to refrigerate the milk.
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Raab et al., Aerztl. Kosmetol., 10(6), Abstract, Chemical Abstract, 14, 109257f (1980).
Merck Index-Properties of natamycin.
D & F Control Systems, Inc.
Johnston Jill A.
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