Milk sample preservative

Chemistry: analytical and immunological testing – Composition for standardization – calibration – simulation,... – Preservative – buffer – anticoagulant or diluent

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422 1, 426326, 4263302, 426335, 426532, 426654, 436 23, 436176, 514 31, A23C 308, G01N 100

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active

051963442

ABSTRACT:
An antimicrobial composition for the preservation of milk samples required for analysis. The composition comprises 2-bromo-2-nitropropane-1,3-diol and natamycin, in effective amounts to prevent spoilage of the milk for a period of at least 5 to 10 days. The amount of 2-bromo-2-nitropropane-1,3-diol for a 50 ml milk sample is preferably 6-12 mg and the amount of natamycin is preferably 0.3-0.6 mg. The composition is preferably employed in the form of a tablet containing a suitable filler and usually other ingredients. In a method of preserving milk samples, the 2-bromo-2-nitropropane-1,3-diol and natamycin may be added separately or simultaneously (e.g. in admixture). The composition and method provide a way of preserving milk samples without the health problems associated with conventional preservatives such as dichromates and without the need to refrigerate the milk.

REFERENCES:
patent: 3558788 (1971-01-01), Clark et al.
patent: 3996386 (1976-12-01), Malkki et al.
patent: 4148891 (1979-04-01), Smink
patent: 4536494 (1985-08-01), Carter
patent: 4636476 (1987-01-01), Brunt et al.
Raab et al., Aerztl. Kosmetol., 10(6), Abstract, Chemical Abstract, 14, 109257f (1980).
Merck Index-Properties of natamycin.

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