Milk-protein hydrolyzates and compositions for use as hair and s

Details Milk-protein hydrolyzates and compositions for use as hair and s Milk-protein hydrolyzates and compositions for use as hair and s

1991-05-17

1994-05-24

Russel, Jeffrey E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

435 681, 530343, 530407, 530832, 530833, A61K 3702, C07K 112, C07K 310

Patent

active

053148738

ABSTRACT:
A milk-protein hydrolyzate consisting of a mixture of peptides and free amino acids having proliferation activating property on human cutaneous cells but not having antigenicity of the milk-protein may be obtained by enzymatic hydrolysis of milk protein. The peptides of the hydrolyzate have molecular weights less than 1000 daltons, and the hydrolyzate has a free aromatic amino acid/total aromatic amino acid ratio of at least 90%. Fractionation of the milk protein hydrolyzate yields a fraction consisting of a mixture of peptides. The fraction has a proliferation activating property on human cutaneous cells but does not have the antigenicity of the milk protein. The fraction contains aromatic amino acids in an amount of less than 5% by weight of total amino acids. Both the hydrolyzate and the fraction can be formulated into cosmetic compositions for application to the hair and skin.

REFERENCES:
patent: 4427658 (1984-01-01), Maubois et al.
patent: 4463017 (1984-07-01), Hidalgo et al.
patent: 4980450 (1990-12-01), Brule et al.
patent: 5112812 (1992-05-01), Samuelsson et al.
Translation of JA 2-138,991 (Published May 28, 1990).

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