Mild solid-phase synthesis of aligned, branched triple-helical p

Details Mild solid-phase synthesis of aligned, branched triple-helical p Mild solid-phase synthesis of aligned, branched triple-helical p

1996-07-03

1998-03-10

Russel, Jeffrey E.

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Mixing of two or more solid polymers; mixing of solid...

530334, 530336, 530337, 530356, 530810, 530812, 530816, C07K 104, C07K 106, C07K 1478, C08G 6910

Patent

active

057262438

ABSTRACT:
A triple-helical polypeptide of the formula: ##STR1## is provided wherein: Z is Hyp or Pro; each X and Y is an amino acid such that (Gly-X-Y).sub.m is a sequence of a collagen cell adhesion site; said X and Y may be the same or different and each (Gly-X-Y) may be the same or different; O is an amino acid having a single side-chain amino group; J is an amino acid capable of acting as a chromophore; U is an amino acid; u=0 or 1; n.ltoreq.30; m.ltoreq.30; m+n.ltoreq.30; and j.gtoreq.1. Methods of making these compounds and intermediates used in the methods, are also provided.

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