Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving hydrolase
Reexamination Certificate
2007-01-02
2007-01-02
Saidha, Tekchand (Department: 1652)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving hydrolase
C435S194000, C435S252300, C435S252330, C435S320100, C435S069200, C536S023200
Reexamination Certificate
active
10245539
ABSTRACT:
The invention provides isolated nucleic acids molecules, designated MID 4460 nucleic acid molecules, which encode novel tyrosine phosphatase family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing MID 4460 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a MID 4460 gene has been introduced or disrupted. The invention still further provides isolated MID 4460 proteins, fusion proteins, antigenic peptides and anti-MID 4460 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.
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Matozaki et al. [J. Biol. Chem. 269 (3): 2075-2081 (1994)].
Sequence alignment between Accession No. A49724 and Applicants'SEQ ID Nos. 2 showing 100% identity.
Sequence alignment between Accession No. D15049 and Applicants'SEQ ID Nos. 1 showing 100% identity.
Takashi Matozaki, et al., “Molecular Cloning of a Human Transmembrane-Type Protein Tyrosine Phosphatase and Its Expression in Gastrointestinal Cancers,” Journal of Biological Chemistry, 269(3); 2075-2081, 1994.
Strausberg, R., Sep. 12, 1997 (sequence) GenBank [online] Bethesda, MD, USA: National Center for Biotechnology Information [retrieved Aug. 19, 2003]. Retrieved from the Internet URL: http://www.ncbi.nlm.nih.gov/>. GenBank Accession No. AA573849.
Strausberg, R., Jul. 13, 2000 (sequence) GenBank [online] Bethesda, MD, USA: National Center for Biotechnology Information [retrieved Aug. 19, 2003]. Retrieved from the Internet URL: http://www.ncbi.nlm.nih.gov/>. GenBank Accession No. BE304621.
Myers, R. M., “Human STS SHGC-10956, Sequence Tagged Site”, Jan. 4, 1996 (sequence) GenBank [online] Bethesda, MD, USA: National Center for Biotechnology Information [retrieved Aug. 19, 2003]. Retrieved from the Internet URL: http://www.ncbi.nlm.nih.gov/>. GenBank Accession No. G13498.
Banner & Witcoff , Ltd.
Bayer Healthcare AG
Saidha Tekchand
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