Chemistry: electrical and wave energy – Apparatus – Electrophoretic or electro-osmotic apparatus
Reexamination Certificate
2005-09-13
2005-09-13
Noguerola, Alex (Department: 1753)
Chemistry: electrical and wave energy
Apparatus
Electrophoretic or electro-osmotic apparatus
C204S601000, C204S603000
Reexamination Certificate
active
06942778
ABSTRACT:
The field of the present invention relates generally to a microstructure apparatus which may be used in a high-throughput screening context to monitor the rate of reaction of an enzyme with its substrate in cases where the product of the reaction has an altered net charge. For example, the systems and methods disclosed herein may be used to detect the activity of phosphatase enzymes, proteases and kinases on charged peptide substrates. The microstructure devices of the present invention comprise a plurality of microstructures, wherein each microstructure comprises a capture matrix located between two electrodes.
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Harper Alan
Havens John
Jalali Shila
Simpson Matt
Swanson Paul
Morgan & Lewis & Bockius, LLP
Nanogen Inc.
Noguerola Alex
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