Microspheres useful for therapeutic vascular occlusions and inje

Details Microspheres useful for therapeutic vascular occlusions and inje Microspheres useful for therapeutic vascular occlusions and inje

1995-06-06

1997-07-15

Azpuru, Carlos

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424489, 424491, 424492, 424496, 424497, 424500, A61K 914, A61K 916, A61K 950

Patent

active

056481004

ABSTRACT:
The present invention concerns the use of microspheres for therapeutic embolization consisting of a hydrophilic acrylic copolymer coated with a cell adhesion promoter.

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patent: 4990340 (1991-02-01), Hidaka
"Microcarrier Culture of Fibroblastic Cells on Modified Trisacryl Beads", Obrenovitch et al, Biol. Cell (1982), 46,249-256.
"Polyacrylamide Derivatives to the Service of Bioseparations", Boschetti, J of Biochem. & Biophys. Methods, 19(1989) 21-36.
"Synthesis and Copolym. of New Water-solulde Polyiodiuated Acrylic Monomers", Brown et al, Makromiol. Chem., Rapid Commun. 6,503-507 (1985).
Laurent et al., "Etude Histologique de Plusieurs Materiaux D'Embolisation et d'un Nouveau Type de Materiel Spherique et Adhesif," Innovation et Technologie en Biologie et Medecine 10(3): 357-366 (1989).
Mazza et al., "Polymer Design in Dye Chromatography: From the definition of monomers to the evaluation of polymeric supports,"in Protein-Dye Interactions: Developments and Applications, Vijayalaksnmi M.A. ed., Elsevier Appl. Sciences, Elsevier Sci. Publ. Ltd., pp. 126-136 (1989).

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