Microspheres for incorporation of therapeutic substances and met

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes

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264 43, 424 11, 424491, 4284022, 436829, 514 34, 514 37, 514963, A61K 952, A61K 964, B01J 1302

Patent

active

046719547

ABSTRACT:
Novel hydrophilic protein or polypeptide microspheres prepared by dispersing an aqueous solution or dispersion of protein or polypeptide in an organic solvent solution of a high molecular weight polymer to form a stabilized dispersion of microspheres and cross-linking said microspheres with a polyfunctional cross-linking agent.

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A. F. Yapel, Jr.: "Albumen Microspheres: Heat and Chemical Stabilization", Methods in Enzymology, vol. 112, Drug and Enzyme Targeting, Part A, edited by K. J. Widder et al., (1985), Academic Press, Inc., pp. 3-18.

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