Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Reexamination Certificate
2011-06-21
2011-06-21
Chong, Kimberly (Department: 1635)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
C536S024500, C536S024310, C536S024100
Reexamination Certificate
active
07964574
ABSTRACT:
AS-oligonucleotides are delivered in microsphere form in order to induce dendritic cell tolerance, particularly in the non-obese-diabetic (NOD) mouse model. The microspheres incorporate antisense (AS) oligonucleotides. A process includes using an antisense approach to reverse an autoimmune diabetes condition in NOD mice in vivo. The oligonucleotides are targeted to bind to primary transcripts CD40, CD80, CD86 and their combinations.
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Brown Larry R.
Giannoukakis Nick
Gillis Kimberly A.
Trucco Massimo
Baxter Healthcare S.A.
Baxter International Inc.
Chong Kimberly
Marshall & Gerstein & Borun LLP
University of Pittsburgh—of the Commonwealth System of Hi
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