Microscope illumination device and adapter

Details Microscope illumination device and adapter Microscope illumination device and adapter

2006-07-14

2009-06-02

Pritchett, Joshua L (Department: 2872)

Optical: systems and elements

Compound lens system

Microscope

Reexamination Certificate

active

07542203

ABSTRACT:
The present invention is a dark field illumination system including a light source which is fixed on an entrance slit of a condenser and an objective aligned with the condenser such that the objective and the condenser are adjusted to find a focus spot on a sample. The present invention essentially uses structured illumination to achieve an improved illumination system. The present invention also includes a system and method wherein the objective is coupled to an iris and aligned with the condenser such that when the iris is closed only dark field images are produced, and when the iris is open, direct entrance of light is allowed into the objective and bright field illumination is produced.

REFERENCES:
patent: 2674157 (1954-04-01), Heine
patent: 2002/0135871 (2002-09-01), Vodyanoy et al.
patent: 2005/0237605 (2005-10-01), Vodyanoy
patent: 89 05 951 (1989-06-01), None
patent: 1 324 096 (2003-07-01), None
patent: WO 00/16151 (2000-03-01), None
patent: WO 2000/37977 (2000-06-01), None
patent: WO 01/35143 (2001-05-01), None
patent: WO 01/57565 (2001-08-01), None
patent: WO 01/61324 (2001-08-01), None
patent: WO 02/061485 (2002-08-01), None
patent: WO 2004/0131816 (2004-04-01), None
patent: WO 2007/046021 (2007-04-01), None
patent: WO 2007/046188 (2007-04-01), None
patent: WO 2007/050470 (2007-05-01), None
patent: WO 2007/076578 (2007-07-01), None
patent: WO 2007/077373 (2007-07-01), None
patent: WO 2007/085721 (2007-08-01), None
patent: WO 2007/088529 (2007-08-01), None
patent: WO 2007/094845 (2007-08-01), None
patent: WO 2007/094987 (2007-08-01), None
patent: WO 2007/095029 (2007-08-01), None
patent: WO 2007/095037 (2007-08-01), None
patent: WO 2007/103436 (2007-09-01), None
patent: WO 2007/111973 (2007-10-01), None
patent: WO 2007/118418 (2007-10-01), None
patent: WO 2007/142846 (2007-12-01), None
patent: WO 2008/069253 (2008-06-01), None
L.C. Martin, An Introduction to Applied Optics. V. 2 (Pitman & Sons, London 1932).
S.W. Hell, “Toward Flourescence Nanoscopy,” Nature Biotechnol. 21, 1347 (2003).
Y. Garini, B.J. Vermolen & I.T. Yong, “From Micro to Nano: Recent Advances in High-Resolution Microscopy,” Curr. Opin. Biotechnol. 16, 3 (2005).
V. Westphal & S.W. Hell, “Nanoscale Resolution in the Focal Plane of an Optical Microscope,” Phys. Rev. Lett. 94, 143903 (2005).
M.G.L. Gustafsson, “Nonlinear Structured-Illumination Microscopy: Widefield Fluorescence Imaging with Theoretically Unlimited Resolution,” PNAS 102, 13081 (2005).
M. Schrader, M. Kozubek, S.W. Hell, & T. Wilson, “Optical Transfer Functions of 4Pi Confocal Microscopes: Theory and Experiment,” Opt. Lett. 22, 436 (1997).
T.M. Richardson, “Test Slides: Diatoms to Divsions—What Are You Looking At? Part 1,” Proc. Roy. Microsc. Soc. 33, 3(1998).
M. Born & E. Wolf. Principles of Optics (Cambridge University Press, 7thed. 1999).
L.C. Martin. The Theory of the Microscope (Elsevier, New York, 1966).
H.H. Hopkins, “Some Problems in the Diffraction Theory of Optical Instruments,” Sci. J. Roy. College 20, 100 (1949).
Thaxton, CS & Mirkin, CA, “Plasmon Coupling Measures Up,” Nature Biotechnology, vol. 23, No. 6, Jun. 2005, 681-2.
Rothenhausler, B. & Knoll, W., “Surface—Plasmon Microscopy,” Nature, vol. 332, Apr. 14, 1988, 615-7.
So, P., “Resolution Enhancement in Standing-Wave Total Internal Reflection Microscopy: A Point-Spread-Function Engineering Approach,” J. Opt. Soc. Am.A., vol. 18, No. 11, Nov. 2001.
Ben-Aryeh, Y. et al., “Increase of Optical Resolution by Evanescent Waves,” Physics Letters A, 328(2004), 306-312.
Frohn, J.T. et al., “True Optical Resolution Beyond the Rayleigh Limit Achieved by Standing Wave Illumination,” PNAS, vol. 97, No. 13, Jun. 20, 2000, 7232-6.
Rajgarhia, Santosh Kumar, Rotate Head On/Off LED Torch With Magnifier Lens, 1128/DEL/2007, Feb. 13, 2009 (Abstract).
Lewis, David E., An Apparatus for Moving an Optical Head from an Initial Track to a Target Track on a Storage Medium, 524/DEL/1999, Jan. 23, 2009, (Abstract).

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