Microscope examination method, optical stimulation...

Details Microscope examination method, optical stimulation... Microscope examination method, optical stimulation...

2007-09-04

2007-09-04

Porta, David (Department: 2884)

Radiant energy

Luminophor irradiation

C250S459100

Reexamination Certificate

active

11129471

ABSTRACT:
While carrying out microscope examination, it is possible to specify a position to be irradiated with optical stimulus light and to accurately apply an optical stimulus to the specified irradiation position. A microscope examination method includes a step of introducing into a specimen a substance in which a structural change is caused by irradiation with light of a first wavelength; a step of specifying an optical stimulation site in the specimen by irradiating the specimen with visible light of a second wavelength that does not cause a structural change in the substance, while examining the specimen in which the substance is introduced using a microscope examination apparatus; and a step of irradiating the specified optical stimulus site with the light of the first wavelength.

REFERENCES:
patent: 2003/0155527 (2003-08-01), Natori
patent: 2004/0001196 (2004-01-01), Shibazaki et al.
patent: 2004/0061073 (2004-04-01), Kitagawa
Atsushi Miyawaki, et al.: Special Review, Optical Techniques Using the New Fluorescent Protein Kaede, Saibou Kougaku (Cell Technology), vol. 22, No. 3, 2003, pp. 316-326.

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