Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form
Reexamination Certificate
2005-10-04
2005-10-04
Page, Thurman K. (Department: 1615)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Particulate form
C424S400000, C424S450000, C264S004000, C264S004100, C264S005000
Reexamination Certificate
active
06951656
ABSTRACT:
The present invention provides a method for preparing submicron sized particles of an organic compound, the solubility of which is greater in a water-miscible first solvent than in a second solvent which is aqueous, the process including the steps of: (i) dissolving the organic compound in the water-miscible first solvent to form a solution, (ii) mixing the solution with the second solvent to define a pre-suspension; and (iii) adding energy to the pre-suspension to form particles having an average effective particle size of less than about 2 μm.
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pat
Brynjelsen Sean
Doty Mark J.
Kipp James E.
Rebbeck Christine L.
Wong Joseph Chung Tak
Baxter International Inc.
Fuchs Joseph A.
Mayo Michael C.
Oh Simon J.
Page Thurman K.
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